Results 101 to 110 of about 6,366 (244)

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Changes in left ventricular systolic and diastolic function after chemotherapy for breast cancer with doxorubicin

Сибирский онкологический журнал
Introduction. Detection of the cardiotoxic effect during chemotherapy (CT) for malignant neoplasms is one of the most important tasks of a practicing physician.
I. A. Karput, V. A. Snezhitskii, M. N. Kurbat, V. A. Gorustovich, Yu. I. Karpovich, A. Yu. Rubinskii, T. A. Smirnova, A. S. Babenka   +7 more
doaj   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Pregnancy and Cardiomyopathy After Anthracyclines in Childhood

, 2018
With advances in cancer therapy, there has been a remarkable increase in survival in children diagnosed with malignancies. Many of these children are treated with anthracyclines which are well known to cause cardiotoxicity.
Kara Annette Thompson
core   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Pharmacological interventions to prevent cardiotoxicity in patients undergoing anthracycline-based chemotherapy: a network meta-analysis

Frontiers in Cardiovascular Medicine
BackgroundThis study evaluates the efficacy of various pharmacological therapies in mitigating the cardiotoxicity associated with anthracycline chemotherapy and furnishes contemporary, evidence-based guidelines and recommendations for clinical practice ...
Xiaoyu Liu, Ran Ding, Aihua Zhang
doaj   +1 more source

Fluorescence of anthracyclines from cultured cells

, 1989
Investigation on the fluorescence properties of optically excited anthracyclines antitumor ...
COLASANTI, ALBERTO, A. von Kisslinger, RUSSO, PAOLO, ANDREONI, ALESSANDRA MARIA, ROBERTI, GIUSEPPE, M. Mastrocinque   +5 more
core  

Anthracyclines: The Double Edged Sword

, 2020
Anthracyclines: The Double Edged Sword Joel Brooks Tamayo Joel, MD, Internal Medicine, Kendall Regional Medical Center. Daniel Gonzalez, MD, Internal Medicine, Kendall Regional Medical Center.
Brooks Tamayo, Joel
core  

Anthracyclines : molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

, 2004
The clinical use of anthracyclines like doxorubicin and daunorubicin can be viewed as a sort of double-edged sword. On the one hand, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases; on the other hand, chronic ...
Luca Gianni, P. Menna, E. Salvatorelli, L. Gianni, G. Cairo, Giorgio Minotti, Gaetano Cairo, G. Minotti, Emanuela Salvatorelli, Pierantonio Menna   +9 more
core   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source