Results 81 to 90 of about 47,221 (287)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon +9 more
wiley +1 more source
Risk factors and prevention of cardiovascular complications in breast cancer
Кардиоваскулярная терапия и профилактикаBreast cancer (BC) is the most common malignant tumor in women. In patients who have undergone antitumor treatment at an early stage of BC, death in the long term more often occurs from cardiovascular diseases (CVD) than from cancer.
M. N. Mamedov +3 more
doaj +1 more source
Characteristics of patients with haematological and breast cancer (1996–2009) who died of heart failure-related causes after cancer therapy [PDF]
, 2016 Aims: To describe the characteristics and time to death of patients with breast or haematological cancer who died of heart failure (HF) after cancer therapy.
Atherton, John +8 more
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Cardiac MRI for differentiating chemotherapy-induced cardiotoxicity in sarcoma and breast cancer
Radiology and OncologyOver the past few decades, many studies have focused on anthracyclines effect on the heart (cardiotoxicity), but only a few have focused on sarcoma.
Ibrahim El-Sayed H +5 more
doaj +1 more source
, 2012 By studying the literature about Tetracyclines (TCs), it becomes clearly evident that TCs are very dynamic molecules. In some cases, their structure-activity-relationship (SAR) are known, especially against bacteria, while against other targets, they are
Bortolotto +17 more
core +2 more sources
Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia
BMEMat, EarlyView.CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai +14 more
wiley +1 more source
Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy [PDF]
, 2017 BCL-2 family proteins are central regulators of mitochondrial apoptosis and validated anti-cancer targets. Using small cell lung cancer (SCLC) as a model, we demonstrated the presence of differential addiction of cancer cells to anti-apoptotic BCL-2, BCL-
Chen, Hui-Chen +13 more
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Chemistry – A European Journal, EarlyView.Experimental and computational studies elucidate how the electronic nature of substituents controls the ring‐opening temperature and diradical character of 1‐substituted benzocyclobutenes, enabling the rational design of o‐quinodimethane‐based synthetic transformations.
Magali Dallegre +8 more
wiley +1 more source
Enhancing the efficacy of cytotoxic agents for cancer therapy using photochemical internalisation. [PDF]
, 2015 Photochemical internalisation (PCI) is a technique for improving cellular delivery of certain bioactive agents which are prone to sequestration within endolysosomes.
Adigbli +69 more
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ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo +10 more
wiley +1 more source