Results 81 to 90 of about 6,366 (244)
La cardiotoxicité des anthracyclines : mécanismes et cibles pharmacologiques de prévention
, 2007 Les anthracyclines sont des agents antitumoraux très largement utilisés en cancérologie. Toutefois, un certain nombre d'effets secondaires, et notamment sur la fonction cardiaque, limitent leur utilisation.
Nathalie Andrieu-Abadie
core +1 more source
Intensive Induction in AML in the Era of Venetoclax: A Standing Count for “7 + 3”?
American Journal of Hematology, EarlyView.
Sudhir Tauro, Ayalew Tefferi
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang +10 more
wiley +1 more source
Cardiac toxicity of antineoplastic anthracyclines
, 2003 Anthracyclines play a major role in the treatment of solid malignancies, but their clinical use is limited by acute or chronic cardiac toxicity. This is not due to the same molecular action involved in the antineoplastic effect, i.e.
DANESI, ROMANO, ZUCCHI, RICCARDO
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Journal of Applied Toxicology, EarlyView.ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan +3 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching +2 more
wiley +1 more source
ORIGINAL ARTICLE Childhood Malignancy and Cardiotoxicity of Anthracyclines
, 2012 Background: Anthracyclines are antitumor agents with broad spectrum activity against many childhood malignancies. An important side effect of these drugs is cardiotoxicity which may happen even years after discontinuation.
Assistant Professor, MD, Pediatric Rouhangiz Sorkhabi +14 more
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Nail Toxicities Associated With Anticancer Therapies in Children
JEADV Clinical Practice, EarlyView.ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley +1 more source
Dose optimization of anthracyclines
, 1994 Despite the fact that anthracyclines are one of the most commonly used and active classes of anticancer agents and that their pharmacokinetic behavior has been extensively studied, optimal anthracycline dosage regimens have not. yet been defined.
de Valeriola, Dominique
core
Cardiac dysfunction in cancer survivors unmasked during exercise [PDF]
, 2016 Introduction: The cardiac dysfunction associated with anthracycline-based chemotherapy cancer treatment can exist sub-clinically for decades before overt presentation.
Gallop-Evans, Eve +11 more
core +1 more source