Results 151 to 160 of about 34,211 (250)

From signal to significance: characterizing anthracycline-related hypercoagulable adverse events via pharmacovigilance, animal models, and clinical observation. [PDF]

Front Pharmacol
Huang W, Shen J, Zhang J.
europepmc   +1 more source

Comparative Phenotypic and Molecular Characterisation of Feline Oral Squamous Cell Carcinoma Cell Lines Reveals Marked Biological Heterogeneity

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Feline oral squamous cell carcinoma (FOSCC) is the most common oral malignancy, characterised by aggressive local invasion, frequent bone involvement, and poor prognosis. The limited availability of well‐characterised in vitro models has hindered the understanding of tumour heterogeneity and invasive behaviour.
Qaisar Tanveer, Lisa Y. Pang, Colin Farquharson, Gurå Therese Bergkvist   +3 more
wiley   +1 more source

Cardiac safety of L-Annamycin: a pooled analysis of five clinical trials. [PDF]

Front Cardiovasc Med
Zalaquett Z, Waymack S, Collier P.
europepmc   +1 more source

Postexercise muscle oxygen uptake kinetics in older breast cancer survivors and healthy individuals: Association with myosteatosis

Experimental Physiology, EarlyView.
Abstract Reduced cardiorespiratory fitness is common among breast cancer survivors and, although traditionally attributed to cardiac dysfunction, might also be related to peripheral skeletal muscle abnormalities. We examined peak and submaximal plantar‐flexion exercise and recovery kinetics for lower‐leg oxygen uptake (V̇O2${\dot V_{{{\mathrm{O}}_2}}}$)
Nathan R. Weeldreyer, Thomas J. McMurtry, Stephen J. Foulkes, Amanda Shewman, Edith Pituskin, Rachel J. Skow, Richard B. Thompson, Justin Grenier, Deirdre E. O'Neill, Robert C. Welsh, Mark J. Haykowsky, Corey R. Tomczak   +11 more
wiley   +1 more source

The Quest for a Safer Use of Anthracyclines Continues: Risk Prediction of Clinical Cardiotoxicity. [PDF]

JACC CardioOncol
Gabizon AA, Levenson JE.
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Three-Dimensional Left Ventricle Strain Echocardiography in the Detection of Anthracycline Cardiotoxicity in Children with Acute Lymphoblastic Leukemia-Retrospective Case-Control Analysis and Relation to the Cardiotoxicity Risk Factors Assessment. [PDF]

Cancers (Basel)
Haponiuk-Skwarlińska J, Kamińska H, Gąsior JS, Albrecht K, Łaguna P, Werner B.   +5 more
europepmc   +1 more source

Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity

, 2012
Anthracyclines play an important role in treatment of variety types of cancer due to their high effectiveness and broad spectrum of activity. However, a major limitation of their use is the dose-limiting cardiotoxicity.
Nikolaev, V.G., Posokhova, E.A., Shevchuk, O.O., Sakhno, L.A.   +3 more
core  

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Anthracycline-containing versus anthracycline-free carboplatin-based regimens in early-stage triple-negative breast cancer: real-world outcomes. [PDF]

Breast Cancer Res Treat
Kroll MR, Schroeder MC, Neuner JM, Viyyuri BR, Ravindra A, McDougall D, Chapman CG, Fleege NMG, Chrischilles EA, Song X, Phadke S.   +10 more
europepmc   +1 more source