Examining Cardiotoxicity With HER2 Therapies∗
Neelima Denduluri, MD
doaj +1 more source
Protective effects of beta-blockers against anthracycline- and trastuzumab-related cardiotoxicity: a systematic review based on conventional and Bayesian network meta-analysis. [PDF]
Jiang S, Gao G.
europepmc +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
Left ventricular function and its longitudinal change in Swiss childhood cancer survivors - results from the CardioOnco study. [PDF]
Fankhauser S +11 more
europepmc +1 more source
Clinical Evidence for Three Distinct Gastric Cancer Subtypes: Time for a New Approach [PDF]
Bearzi Italo +10 more
core +1 more source
ABSTRACT Primary refractory Diffuse Large B‐Cell Lymphoma is associated with poor outcomes and limited responsiveness to conventional salvage therapies. Although CAR T‐cell therapy represents the standard of care in this setting, a substantial proportion of patients cannot receive it despite meeting disease‐related criteria. In this review, “unsuitable”
Santino Caserta +12 more
wiley +1 more source
An echocardiographic study of right ventricular function and pulmonary systolic pressure in patients treated with anthracyclines. [PDF]
Ozan R +10 more
europepmc +1 more source
Prognostic impact of ASXL1 mutations in acute myeloid leukemia treated with lower intensity therapy
Abstract Background ASXL1 mutations (ASXL1MUT) are common in acute myeloid leukemia (AML) and have historically conferred an adverse prognosis with intensive chemotherapy. Given the increasing use of venetoclax (VEN)‐based lower intensity therapy (LIT), the European LeukemiaNet introduced a four‐gene genetic risk classifier in 2024 that categorizes ...
Jennifer Marvin‐Peek +26 more
wiley +1 more source
Comparing efficacy of neoadjuvant therapy of triple-negative breast cancer: A Bayesian network meta-regression analysis. [PDF]
Jiang Y +8 more
europepmc +1 more source
ABSTRACT Over the past decade, clonal hematopoiesis (CH) has gained substantial attention as a prevalent, age‐associated phenomenon with major implications for hematologic malignancy, cardiovascular disease, and mortality. CH arises from the clonal expansion of hematopoietic stem cells and progenitor cells harboring somatic mutations, most commonly in ...
Christian H. Nenninger +7 more
wiley +1 more source

