Results 81 to 90 of about 46,290 (201)

Postexercise muscle oxygen uptake kinetics in older breast cancer survivors and healthy individuals: Association with myosteatosis

open access: yesExperimental Physiology, EarlyView.
Abstract Reduced cardiorespiratory fitness is common among breast cancer survivors and, although traditionally attributed to cardiac dysfunction, might also be related to peripheral skeletal muscle abnormalities. We examined peak and submaximal plantar‐flexion exercise and recovery kinetics for lower‐leg oxygen uptake (V̇O2${\dot V_{{{\mathrm{O}}_2}}}$)
Nathan R. Weeldreyer   +11 more
wiley   +1 more source

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero   +7 more
wiley   +1 more source

Clinical validation of a DNA methylation biomarker associated with overall survival of relapsed ovarian cancer patients

open access: yesInternational Journal of Cancer, Volume 158, Issue 7, Page 1821-1835, 1 April 2026.
What's new? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman   +7 more
wiley   +1 more source

Randomized Comparison of Cardiotoxicity With 60 Versus 90 mg Daunorubicin in AML Induction Therapy

open access: yesAmerican Journal of Hematology, Volume 101, Issue 3, Page 512-520, March 2026.
Early cardiac biomarker monitoring in AML induction therapy showed significantly higher hsTnT levels after daunorubicin 90 mg/m2 compared with 60 mg/m2, indicating a dose‐dependent early myocardial effect. ABSTRACT Anthracyclines are an essential component of induction therapy for acute myeloid leukemia (AML), but their optimal dosing and the ...
Stefan Markus Dendorfer   +44 more
wiley   +1 more source

Protein Energy Malnutrition: Opportunities for Cold Plasma Technologies

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Protein energy malnutrition (PEM) is a major global health concern driven by biological, environmental, and nutritional factors, including gut microbiota imbalance and low protein intake. Cold atmospheric plasma technologies offer promising, sustainable solutions by improving food security, enhancing protein quality and absorption, and modulating gut ...
Karthika Prasad   +6 more
wiley   +1 more source

Cancer drugs and the heart: importance and management [PDF]

open access: yes, 2017
Progress in the detection and treatment of cancer has led to an impressive reduction in both mortality and morbidity. Due to their mechanism of action, however, conventional chemotherapeutics and some of the newer anti-cancer signaling inhibitors carry a
Ewer, Michael S., Suter, Thomas M.
core  

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

open access: yesJournal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto   +6 more
wiley   +1 more source

Cancer Comorbidities: Clinical Impacts, Mechanistic Insights, and Management Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review focuses on cancer comorbidities, examining their clinical impacts and mechanistic insights. It further examines key management challenges, including evidence gaps, the lack of precise assessment tools, limited management frameworks, and underdeveloped multidisciplinary collaborations.
Taoxing Peng   +15 more
wiley   +1 more source

Utility of Cytochemical and Flow Cytometry Detection of Alkaline Phosphatase for Differential Diagnosis of CD34+ Acute Leukaemia in Canines

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 41-50, March 2026.
ABSTRACT Alkaline phosphatase (ALP) enzymatic activity has been proposed as a marker for distinguishing canine acute leukaemia (AL) subtypes (i.e., myeloid vs. lymphoid). However, ALP enzymatic activity has not been fully evaluated in CD34+ AL. Determine whether ALP enzymatic activity can differentiate CD34+ AL subtypes in dogs and distinguish CD34+ AL
Megan Aalto   +7 more
wiley   +1 more source

Development and Testing of an Owner‐Reported Outcome Measure of Clinical Signs and Quality of Life in Dogs Treated With Chemotherapy

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 80-94, March 2026.
ABSTRACT Cancer is a leading cause of mortality in older dogs. Despite the prevalence of chemotherapy in canine oncology, a good understanding of owners' observations of side effects and clinical signs in real time is still lacking. Owners' perceptions and reporting of clinical signs play an important role in monitoring a dog's condition during ...
Jenny Harris   +5 more
wiley   +1 more source

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