Results 121 to 130 of about 8,844 (171)
A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. [PDF]
Am J Med Genet A, 2018 Dinckan N +16 more
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The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure. [PDF]
Sci Rep, 2019 Cheng B +7 more
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Infectious bacteria as biological warfare agents: mechanisms, epidemiological threats, and defense strategies. [PDF]
Front Bioeng BiotechnolShah K, Khan MI, Guo Y, Adnan M, Wu H.
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Targeted Silencing of Anthrax Toxin Receptors Protects against Anthrax Toxins [PDF]
Journal of Biological Chemistry, 2014 Anthrax spores can be aerosolized and dispersed as a bioweapon. Current postexposure treatments are inadequate at later stages of infection, when high levels of anthrax toxins are present. Anthrax toxins enter cells via two identified anthrax toxin receptors: tumor endothelial marker 8 (TEM8) and capillary morphogenesis protein 2 (CMG2).
Shan Chen +2 more
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Cellular and Molecular Life Sciences (CMLS), 1999
Though its lethal effects were ascribed to an exotoxin almost half a century ago, the pathogenesis of anthrax has yet to be satisfactorily explained. Subsequent work has led to the molecular identification and enzymatic characterization of three proteins that constitute two anthrax toxins.
N S, Duesbery, G F, Vande Woude
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Though its lethal effects were ascribed to an exotoxin almost half a century ago, the pathogenesis of anthrax has yet to be satisfactorily explained. Subsequent work has led to the molecular identification and enzymatic characterization of three proteins that constitute two anthrax toxins.
N S, Duesbery, G F, Vande Woude
openaire +2 more sources
Receptors of anthrax toxin and cell entry [PDF]
Molecular Aspects of Medicine, 2009 Anthrax toxin-receptor interactions are critical for toxin delivery to the host cell cytoplasm. This review summarizes what is known about the molecular details of the protective antigen (PA) toxin subunit interaction with either the ANTXR1 and ANTXR2 cellular receptors, and how receptor-type can dictate the low pH threshold of PA pore formation.
Gisou Van Der Goot, John A T Young
exaly +4 more sources
Annual Review of Cell and Developmental Biology, 2003
▪ Abstract Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells. One of these proteins, protective antigen (PA), transports the other two, edema factor (EF) and lethal factor (LF), to the cytosol.
R John, Collier, John A T, Young
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▪ Abstract Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells. One of these proteins, protective antigen (PA), transports the other two, edema factor (EF) and lethal factor (LF), to the cytosol.
R John, Collier, John A T, Young
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Critical Reviews in Microbiology, 2001
Anthrax is primarily a disease of herbivores caused by gram-positive, aerobic, spore-forming Bacillus anthracis. Humans are accidental hosts through the food of animal origin and animal products. Anthrax is prevelant in most parts of the globe, and cases of anthrax have been reported from almost every country.
R, Bhatnagar, S, Batra
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Anthrax is primarily a disease of herbivores caused by gram-positive, aerobic, spore-forming Bacillus anthracis. Humans are accidental hosts through the food of animal origin and animal products. Anthrax is prevelant in most parts of the globe, and cases of anthrax have been reported from almost every country.
R, Bhatnagar, S, Batra
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In Vivo–produced Anthrax Toxin
Journal of Bacteriology, 1968Specific anthrax antigens were demonstrated in the blood of animals dying from anthrax. These antigens, which appear in the blood at the time when organisms are first detected and whose concentration continues to increase as the number of organisms increases, do not elicit a strong antibody response. The in vivo-produced toxin differs from the in vitro
D C, Fish, R E, Lincoln
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