Results 101 to 110 of about 10,314 (165)

Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis. [PDF]

open access: yesFront Cell Dev Biol, 2023
Huang X   +7 more
europepmc   +1 more source

Anthrax toxin: a tripartite lethal combination

open access: yes, 2002
Anthrax is a severe bacterial infection that occurs when Bacillus anthracis spores gain access into the body and germinate in macrophages, causing septicemia and toxemia.
VISCA P   +5 more
core  

Neutrophil Elastase Mediates Pathogenic Effects of Anthrax Lethal Toxin in the Murine Intestinal Tract

open access: yes, 2010
Neutrophils isolated from BALB/c or C57BL/6 mice and treated in vitro with anthrax lethal toxin release bioactive neutrophil elastase, a proinflammatory mediator of tissue destruction. Similarly, neutrophils isolated from mice treated with anthrax lethal
Roger D. Auth   +6 more
core   +1 more source

Antibodies against protective antigen and methods of use for passive immunization and treatment of anthrax

open access: yes, 2008
A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to
Jiang, I.   +6 more
core  

Inhibition of platelet aggregation by anthrax edema toxin

open access: yes, 2006
Edema toxin is a key virulence determinant in anthrax pathogenesis that causes augmentation of cAMP inside host cells. This exotoxin has been implicated in facilitating bacterial invasion by impairing host defenses.
Bhatnagar, Rakesh   +2 more
core   +1 more source

Multiple stages of evolutionary change in anthrax toxin receptor expression in humans. [PDF]

open access: yesNat Commun, 2021
Choate LA   +7 more
europepmc   +1 more source

Delivery of nucleic acid into mammalian cells by anthrax toxin

open access: yes, 2002
Gene delivery vehicles based on receptor-mediated endocytosis offer an attractive long-term solution as they might overcome the limitations of toxicity and cargo capacity inherent to many viral gene delivery systems.
Wels, Winfried   +4 more
core   +1 more source

Catalytically inactive anthrax toxin(s) are potential prophylactic agents

open access: yes, 2007
The anthrax exotoxin, which is a key mediator of anthrax related pathogenesis, is composed of two separate toxins formed by pairwise combinations of three proteins that are encoded on the pXO1 plasmid of Bacillus anthracis.
Bhatnagar, Rakesh   +5 more
core   +1 more source

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