Results 91 to 100 of about 10,314 (165)
Anthrax: Transmission, Pathogenesis, Prevention and Treatment
ToxinsBacillus anthracis is a deadly pathogen that under unfavourable conditions forms highly resistant spores which enable them to survive for a long period of time. Spores of B.
Nitika Sangwan +7 more
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Cytoskeleton as an Emerging Target of Anthrax Toxins
Toxins, 2012 Bacillus anthracis, the agent of anthrax, has gained virulence through its exotoxins produced by vegetative bacilli and is composed of three components forming lethal toxin (LT) and edema toxin (ET).
Jean-Nicolas Tournier, Yannick Trescos
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, 2020 (A) 50% effective dilution (ED50) values for serum neutralization of Lethal Toxin (LT) determined in a J774A.1 macrophage-based LT neutralization assay using serum from cutaneous anthrax survivors (n = 46) compared to regional healthy controls with no ...
Jimmy D. Ballard (8714277) +13 more
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Deletion mutants of protective antigen that inhibit anthrax toxin both in vitro and in vivo
, 2003 The anthrax toxin complex is primarily responsible for most of the symptoms of anthrax. This complex is composed of three proteins, anthrax protective antigen, anthrax edema factor, and anthrax lethal factor.
Bhatnagar, Rakesh +4 more
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Raxibacumab: potential role in the treatment of inhalational anthrax
Infection and Drug Resistance, 2014 Carlos E KummerfeldtDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC, USAAbstract: Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an ...
Kummerfeldt CE
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LRP6 Holds the Key to the Entry of Anthrax Toxin
, 2006 In this issue of Cell, Wei et al. (2006) demonstrate that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells.
Bann, James G. +2 more
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BMC Infectious Diseases, 2018 Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage.
Qi Tang +7 more
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Anthrax Toxin Delivers a One-Two Punch
, 2010 Although anthrax toxin was identified as a major Bacillus anthracis virulence factor over 50 years ago, defining the physiologically relevant targets has been challenging. Liu et al.
Kenneth A. Bradley +3 more
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, 2001 Anthrax is primarily a disease of herbivores caused by Gram-positive, aerobic, spore-forming Bacillus anthracis. Humans are accidental hosts through the food of animal origin and animal products. Anthrax is prevelant in most parts of the globe, and cases
Bhatnagar, Rakesh, Batra, Smriti
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Anthrax Toxins in Context of Bacillus anthracis Spores and Spore Germination
Toxins, 2015 The interaction of anthrax toxin or toxin components with B. anthracis spores has been demonstrated. Germinating spores can produce significant amounts of toxin components very soon after the initiation of germination.
Christopher K. Cote, Susan L. Welkos
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