Results 91 to 100 of about 142,050 (194)

Anthrax: Transmission, Pathogenesis, Prevention and Treatment

Toxins
Bacillus anthracis is a deadly pathogen that under unfavourable conditions forms highly resistant spores which enable them to survive for a long period of time. Spores of B.
Nitika Sangwan, Aakriti Gangwal, Preksha Jain, Chokey Langtso, Shruti Srivastava, Uma Dhawan, Renu Baweja, Yogendra Singh   +7 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Raxibacumab: potential role in the treatment of inhalational anthrax

Infection and Drug Resistance, 2014
Carlos E KummerfeldtDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC, USAAbstract: Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an ...
Kummerfeldt CE
doaj  

Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax

BMC Infectious Diseases, 2018
Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage.
Qi Tang, Siping Xiong, Xudong Liang, Xingwang Kuai, Yiwen Wang, Changjun Wang, Zhenqing Feng, Jin Zhu   +7 more
doaj   +1 more source

Anthrax toxin receptor drives protective antigen oligomerization and stabilizes the heptameric and octameric oligomer by a similar mechanism.

PLoS ONE, 2010
BackgroundAnthrax toxin is comprised of protective antigen (PA), lethal factor (LF), and edema factor (EF). These proteins are individually nontoxic; however, when PA assembles with LF and EF, it produces lethal toxin and edema toxin, respectively ...
Alexander F Kintzer, Harry J Sterling, Iok I Tang, Evan R Williams, Bryan A Krantz   +4 more
doaj   +1 more source

Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis. [PDF]

Front Cell Dev Biol, 2023
Huang X, Zhang L, Luo W, Zeng Y, Li X, Yang N, Huang W, Ding BS.   +7 more
europepmc   +1 more source

Treatment of ovarian cancer with modified anthrax toxin. [PDF]

Proc Natl Acad Sci U S A, 2022
Aktories K.
europepmc   +1 more source

DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin. [PDF]

Sci Rep, 2023
Becker L, Plückthun A.
europepmc   +1 more source

BPTES inhibits anthrax lethal toxin-induced inflammatory response

, 2020
Bacillus anthracis is a lethal agent of anthrax disease and the toxins are required in anthrax pathogenesis. The anthrax lethal toxin can trigger NLRP1b inflammasome activation and pyroptosis.
Shen, Xizi, Zhong, Jiaying, Zhao, Yilin, Wang, Jinling, Liu, Xiaomei, Wang, Junsheng, Lin, Jinzhou, Qi, Zhongquan, Yang, Daowei   +8 more
core   +1 more source

Multiple stages of evolutionary change in anthrax toxin receptor expression in humans. [PDF]

Nat Commun, 2021
Choate LA, Barshad G, McMahon PW, Said I, Rice EJ, Munn PR, Lewis JJ, Danko CG.   +7 more
europepmc   +1 more source