Results 81 to 90 of about 142,050 (194)
Metagenomic analysis identified 27 pathogenic bacteria including 4 "ESKAPE" pathogens (Enterobacter sp., Staphylococcus aureus, Klebsiella spp., and Escherichia coli) and numerous organisms associated with ocular infections. A broad range of antimicrobial resistance genes were identified conveying resistance to Methicillin, Aminoglycosides, Macrolides,
Adrian Goldsworthy +8 more
wiley +1 more source
Pinpointing anthrax-toxin inhibitors
Anthrax toxin consists of three components: protective antigen (PA), lethal factor (LF), and edema factor (EF).
Richards, W. Graham +5 more
core +1 more source
Identification of a novel zinc metalloprotease through a global analysis of clostridium difficile extracellular proteins [PDF]
Clostridium difficile is a major cause of infectious diarrhea worldwide. Although the cell surface proteins are recognized to be important in clostridial pathogenesis, biological functions of only a few are known.
Maria Scarselli (247406) +39 more
core +1 more source
Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin
Anthrax is caused by the gram-positive bacterium Bacillus anthracis. The pathogenesis of this disease is dependent on the presence of two binary toxins, edema toxin (EdTx) and lethal toxin (LeTx). LeTx, the major virulence factor contributing to anthrax,
Jennifer Bromberg-White +2 more
doaj +1 more source
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng +10 more
wiley +1 more source
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen +5 more
wiley +1 more source
Micro/nanorobots for detecting and eliminating biological and chemical warfare agents
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li +4 more
wiley +1 more source
A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro
Human anthrax infection caused by exposure to Bacillus anthracis cannot always be treated by antibiotics. This is mostly because of the effect of the remaining anthrax toxin in the body.
Guipeng Ding +5 more
doaj +1 more source
Immunization and treatment methods for anthrax
A highly efficient method for generating human antibodies using recall technology is provided. In one aspect, human antibodies which are specific to the anthrax toxin are provided. In one aspect, human peripheral blood cells that have been pre-exposed to
Jiang, I. +6 more
core
The anthrax toxin channel: a barrel of LFs [PDF]
The use of anthrax as a model system dates back to the late 19th century and Koch’s initial investigations into the transmission of infectious diseases ([Koch, 1877][1]). These studies, coupled with his subsequent investigations into tuberculosis, enabled Koch to formulate the first set of ...
openaire +2 more sources

