Results 51 to 60 of about 24,310,613 (194)

Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome

Frontiers in Immunology, 2019
Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease characterized by arterial and/or venous thrombosis, pregnancy morbidity in the presence of circulating “anti-phospholipid antibodies” (aPL).
Valeria Manganelli, Simona Truglia, Antonella Capozzi, Cristiano Alessandri, Gloria Riitano, Francesca Romana Spinelli, Fulvia Ceccarelli, Silvia Mancuso, Tina Garofalo, Agostina Longo, Guido Valesini, Maurizio Sorice, Fabrizio Conti, Roberta Misasi   +13 more
doaj   +1 more source

Environmental Triggers of Autoreactive Responses: Induction of Antiphospholipid Antibody Formation

Frontiers in Immunology, 2019
Antiphospholipid antibodies (aPLs) comprise a diverse family of autoantibodies targeted against proteins with the affinity toward negatively charged phospholipids or protein-phospholipid complexes.
Anush Martirosyan, Anush Martirosyan, Rustam Aminov, Gayane Manukyan, Gayane Manukyan   +4 more
doaj   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Antibodies against domain I of β2-glycoprotein I: the one and only?

, 2012
The antiphospholipid syndrome (APS) is diagnosed by the occurrence of thrombosis and/or specific pregnancy morbidity. However, the diagnosis of APS is not easy and is hampered by several problems including high prevalence of clinical symptoms and high ...
L Pelkmans, B de Laat, de laat, B., Pelkmans, L, de Laat, B, Pelkmans, L.   +5 more
core   +1 more source

Is it necessary to perform connective tissue disorders laboratory tests when a patient experiences the first demyelinating attack?

Journal of Research in Medical Sciences, 2013
Background: It may be difficult to differentiate between the first demyelinating attack and the neurological manifestations of connective tissue diseases.
Masoud Etemadifar, Alimohammad Fatemi, Hourossadat Hashemijazi, Amir Kazemizadeh   +3 more
doaj  

Comparative analysis of prothrombotic activity in patients with myocardial infarction with and without obstructive coronary artery disease

Российский кардиологический журнал, 2021
Aim. To compare parameters of prothrombotic activity in patients with myocardial infarction (MI) with obstructive (MICAD) and non-obstructive coronary artery disease (MINOCA).Material and methods.
D. A. Vorobieva, Yu. G. Lugacheva, N. A. Kapilevich, V. V. Ryabov   +3 more
doaj   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Expression of anticardiolipin cofactor, human β2-glycoprotein I, by a recombinant baculovirus/insect cell system

, 1993
SUMMARY A full-length cDNA coding a human β2-glycoprotein I (β2-GPI) was introduced into the baculovirus genome to construct a recombinant baculovirus. Spodoptera frugiperda (Sf9) cells were infected with the recombinant baculovirus.
E MATSUURA, H NAGAE, M IGARASHI, T YASUDA, Y IGARASHI, D R VOELKER, K ICHIKAWA, Y MATSUURA, T KOIKE   +8 more
core   +1 more source

Possible Association of Etanercept, Venous Thrombosis, and Induction of Antiphospholipid Syndrome

Case Reports in Rheumatology, 2014
Tumor necrosis factor α (TNF α) inhibitors are commonly used for treatment of aggressive rheumatoid arthritis and other rheumatic diseases. Etanercept is one of the medications approved for treatment of rheumatoid arthritis.
Shanti Virupannavar, Anthony Brandau, Carla Guggenheim, Heather Laird-Fick   +3 more
doaj   +1 more source

Reassessing the role of antiphospholipid antibodies in placental‐mediated adverse pregnancy outcomes in systemic lupus erythematosus: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang, Yanling Chang, Ning Zhang, Wen Di, Jiayue Wu   +4 more
wiley   +1 more source