Results 61 to 70 of about 24,310,613 (194)

Antibodies to age-β2 glycoprotein I in patients with antiphospholipid antibody syndrome.

, 2016
Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease clinically characterized by arterial and/or venous thromboses, recurrent abortions or fetal loss and serologically by the presence of "antiphospholipid antibodies" (aPL).
B Buttari, Facchiano, F, R Misasi, A Capozzi, Buttari, B, CAPOZZI, ANTONELLA, CONTI, FABRIZIO, S Truglia, F Facchiano, F Conti, R Riganò, G Valesini, Riganò, R., RECALCHI, SERENA, C Alessandri, Profumo, E, ALESSANDRI, cristiano, S Recalchi, MISASI, Roberta, SORICE, Maurizio, VALESINI, Guido, M Sorice, E Profumo, TRUGLIA, SIMONA   +23 more
core   +1 more source

Anti-β2-glycoprotein I autoantibodies influence thrombin generation parameters via various mechanisms [PDF]

, 2020
Introduction Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterised by recurrent thrombotic events, pregnancy loss and thrombocytopenia and the presence of antiphospholipid antibodies (APL).
Kappelmayer, János, Østerud, Bjarne, Tarr, Tünde, Soltesz, P., Szabó, Gábor, Debreceni, Ildikó Beke, Pál Soltész, János Kappelmayer, Gábor Szabó, Tünde Tarr, Ildikó Beke Debreceni, Bjarne Østerud   +11 more
core   +1 more source

Antiphospholipid Syndrome and Lupus Anticoagulant: Where do we stand today ? [PDF]

Perspectives In Medical Research
Lupus Anticoagulant (LAC) is a group of auto antiantibodies that interfere with phospholipid dependent tests like Activated Partial Thromboplastin time (APTT) and dilute Russell Viper venom time (dRVVT) on in vitro basis. LA, anti cardiolipin antibodies (
Shalini Trivedi, Sarika Verma, Omkaar Kaur, Sonal Agarwal, Udita Singhal, Mily Biswas Singh   +5 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Involvement of β2-glycoprotein I and anticardiolipin antibodies in oxidatively modified low-density lipoprotein uptake by macrophages

, 1997
SUMMARY Anticardiolipin antibodies (aCL) in the sera of patients with antiphospholipid syndrome (APS) recognize an altered structure of β2-glycoprotein I (β2-GPI) interacting with solid-phase negatively charged phospholipids.
S NISHI, E MATSUURA, Z MAKITA, Y HASUNUMA, T KATAHIRA, T KOIKE   +5 more
core   +1 more source

Overview of antiphospholipid antibodies (aPL) and pair-wise statistical testing (AnV, annexin 5; β2, β2-glycoprotein I, IQR, interquartile range; CL, OD, optical density; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PG, phosphatidylglycerol; PI, phosphatidylinositol; PS, phosphatidylserine; PT, prothrombin).

, 2021
Overview of antiphospholipid antibodies (aPL) and pair-wise statistical testing (AnV, annexin 5; β2, β2-glycoprotein I, IQR, interquartile range; CL, OD, optical density; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PG ...
Martin F. Sprinzl (4339777), Vishalini Emmenegger (11790839), Adriano Aguzzi (49294), Marc Emmenegger (11614492), Laura Rose (749727), Karl J. Lackner (7404842), Clemens J. Sommer (11790845), Dirk Roggenbuck (407723), Sreedhar Saseendran Kumar (11790836), Peter Schierack (355803), Tomas Malinauskas (10040777), Thomas Buettner (11790842), Katrin B. M. Frauenknecht (11790848)   +12 more
core   +1 more source

Serum autoantibody panel as a novel predictor for preeclampsia: a nested case-control study

BMC Pregnancy and Childbirth
Background Preeclampsia is a severe pregnancy-related complication that poses a major threat to the health of both mothers and fetuses. Early identification of high-risk pregnant women remains one of the key clinical challenges.
Kai Cheng, Qian Gao, Yuping Duan, Hui Zhang, Leiming Cai, Qian Li   +5 more
doaj   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

A mechanism of development of arterial thrombosis : β2-glycoprotein I-specific ligand and autoantibody [PDF]

, 2002
β2-Glycoprotein I (β2-GPI) is a major antigen for anticardiolipin antibodies (aCL) appeared in patients with antiphospholipid syndrome (APS). We recently reported that β2-GPI specifically binds to oxidized low-density lipoprotein (oxLDL) and that on of ...
Liu, Qingping
core  

Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome

Frontiers in Immunology
ObjectiveAntiphospholipid syndrome (APS) is an autoimmune condition characterized by recurrent thrombosis, pregnancy-related complications and circulating antiphospholipid antibodies, including anti-β2-glycoprotein I (β2-GPI).
Francesca Villani, Antonella Capozzi, Federica Maria Ucci, Simona Truglia, Manuela De Michele, Silvia Mancuso, Luca Rapino, Giuseppe Tripodi, Valeria Manganelli, Gloria Riitano, Roberta Misasi, Maurizio Sorice, Antonio Sili Scavalli, Fabrizio Conti, Cristiano Alessandri   +14 more
doaj   +1 more source