Results 71 to 80 of about 24,310,613 (194)

Factors Associated With Bilateral Involvement in Non‐Infectious Labyrinthitis: A Case–Control Study

The Laryngoscope, EarlyView.
Non‐infectious labyrinthitis may progress from unilateral to bilateral inner‐ear involvement, resulting in greater functional impairment. In this retrospective case–control study of 50 patients, younger age, female sex, and the presence of systemic disease were associated with bilateral involvement. These exploratory findings may help identify patients
Douglas Henderson, Blanca Amador Borrero, Aurélien Cadix, Karine Champion, Damien Sene, Philippe Herman, Charlotte Hautefort, Alain Londero, Michael Eliezer, Cassandre Djian   +9 more
wiley   +1 more source

Autoantibody detection is not recommended for chronic pancreatitis: a cross-sectional Study of 557 patients

BMC Gastroenterology, 2019
Background Autoimmune factor was regarded as one of the risk factors in the pathogenesis of chronic pancreatitis (CP), especially for autoimmune pancreatitis (AIP). However, whether autoimmune factor plays a role in non-AIP CP or not was unknown. Methods
Xiang-Peng Zeng, Ting-Ting Liu, Lu Hao, Lei Xin, Teng Wang, Lin He, Jun Pan, Dan Wang, Ya-Wei Bi, Jun-Tao Ji, Zhuan Liao, Ting-Ting Du, Jin-Huan Lin, Di Zhang, Hong-Lei Guo, Hui Chen, Wen-Bin Zou, Bai-Rong Li, Zhi-Jie Cong, Li-Sheng Wang, Zheng-Lei Xu, Ting Xie, Ming-Hao Liu, An-Mei Deng, Zhao-Shen Li, Liang-Hao Hu   +25 more
doaj   +1 more source

Anti-Phospholipid Antibodies in COVID-19 Are Different From Those Detectable in the Anti-Phospholipid Syndrome

Frontiers in Immunology, 2020
BackgroundCritically ill patients with coronavirus disease 2019 (COVID-19) have a profound hypercoagulable state and often develop coagulopathy which leads to organ failure and death. Because of a prolonged activated partial-thromboplastin time (aPTT), a
Maria Orietta Borghi, Maria Orietta Borghi, Asmaa Beltagy, Asmaa Beltagy, Emirena Garrafa, Emirena Garrafa, Daniele Curreli, Germana Cecchini, Caterina Bodio, Claudia Grossi, Simonetta Blengino, Angela Tincani, Franco Franceschini, Laura Andreoli, Maria Grazia Lazzaroni, Silvia Piantoni, Stefania Masneri, Francesca Crisafulli, Duilio Brugnoni, Maria Lorenza Muiesan, Massimo Salvetti, Gianfranco Parati, Erminio Torresani, Michael Mahler, Francesca Heilbron, Francesca Pregnolato, Martino Pengo, Francesco Tedesco, Nicola Pozzi, Pier Luigi Meroni   +29 more
doaj   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

β2-glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model

, 2011
Antiphospholipid syndrome is characterized by thrombosis, recurrent fetal loss, and the presence of the lupus anticoagulant, anticardiolipin antibodies, or anti–β2-glycoprotein-1 (anti–β2-GP1) antibodies.
Valerie Proulle, Richard A. Furie, Bruce Furie, Barbara C. Furie, Ariela Arad   +4 more
core   +1 more source

Anti-β2GPI/β2GPI complex promotes thrombosis by activating the P2Y2/MAPKs pathway to increase human neutrophil peptides.

PLoS ONE
Anti-β2 glycoprotein I (Anti-β2GPI) antibodies are a heterogeneous group of antiphospholipid antibodies targeting β2 glycoprotein I (β2GPI). High titer of anti-β2GPI antibodies is a risk factor for thrombosis in antiphospholipid syndrome (APS).
Xin Guan, Wen Liu, Tianfeng Gao, Wenying Jin, Yueqiu Gao, Huiyuan Tan, Lujie Guo, Yanfen Zhang   +7 more
doaj   +1 more source

Prevalence of antiphospholipid antibodies in Behçet's disease: A systematic review and meta-analysis.

PLoS ONE, 2020
Behçet's disease (BD) is a multifactorial systemic inflammatory disease of unknown aetiology characterised by several clinical manifestations including vascular involvements (i.e., both arterial and venous thrombosis).
Md Asiful Islam, Sayeda Sadia Alam, Shoumik Kundu, A H M Safayet Ullah Prodhan, Shahad Saif Khandker, Tatiana Reshetnyak, Przemysław J Kotyla, Rosline Hassan, Tareq Hossan   +8 more
doaj   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

β2-glycoprotein I promotes the clearance of circulating mitochondria. [PDF]

β2-glycoprotein I (β2-Gp1) is a cardiolipin-binding plasma glycoprotein. It is evolutionarily conserved from invertebrates, and cardiolipin-bound β2-Gp1 is a major target of antiphospholipid antibodies seen in autoimmune disorders.
Rumbaut, Rolando E, Ross A Poche, Thiagarajan, Perumal, Rolando E Rumbaut, Dasgupta, Swapan Kumar, Swapan Kumar Dasgupta, Stefanie Rivera, Gollamudi, Jahnavi, Rivera, Stefanie, Poche, Ross A, Jahnavi Gollamudi, Perumal Thiagarajan   +11 more
core   +1 more source