Results 111 to 120 of about 12,264,289 (383)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Masculine Vitality: Pros and Cons of Testosterone in Treating the Andropause [PDF]

open access: yes, 2003
As our population ages, concerns about frailty and disability, as well as the all-too-human desire to remain young for as long as possible have led increasing numbers of women and men to the questionable practice of restoring diminishing hormone levels ...
Judith Estrine, Nora O'Brien
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Ordering dynamics in the voter model with aging

open access: yes, 2019
The voter model with memory-dependent dynamics is theoretically and numerically studied at the mean-field level. The `internal age', or time an individual spends holding the same state, is added to the set of binary states of the population, such that ...
Khalil, Nagi   +2 more
core   +1 more source

Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases [PDF]

open access: yes, 2020
Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c] pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring leads to secoiridoids.
Alarcón de la Lastra Romero, Catalina   +3 more
core   +1 more source

BFLIDS: Blockchain-Driven Federated Learning for Intrusion Detection in IoMT Networks

open access: yesSensors
The Internet of Medical Things (IoMT) has significantly advanced healthcare, but it has also brought about critical security challenges. Traditional security solutions struggle to keep pace with the dynamic and interconnected nature of IoMT systems ...
Khadija Begum   +3 more
doaj   +1 more source

Fabrication of a Pneumatic Microparticle Concentrator

open access: yesMicromachines, 2019
We developed a microfluidic platform employing (normally open) pneumatic valves for particle concentration. The device features a three-dimensional network with a curved fluidic channel and three pneumatic valves (a sieve valve (Vs) that concentrates ...
Jun Ho Jang, Ok Chan Jeong
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Neuroprotection in glaucoma using Gouqizi (Wolfberry) [PDF]

open access: yes, 2010
Aging is an important risk factor for various neurodegenerative diseases such as glaucoma and Alzheimer's disease (AD). Glaucoma is a common eye disease that may lead to irreversible blindness.
Chang, RCC, So, KF
core  

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

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