Results 11 to 20 of about 2,808 (150)

Potential of Critical Mineral and Cytotoxicity Activity of Gadolinium Complex as Anti-amoebic Agent by Viability Studies and Flow Cytometry Techniques

AUIQ Complementary Biological System
The screening of lanthanide as a critical mineral and used as an anti-amoebic agent is important to identify the safest method and mode of cell death to eliminate this microorganism from the host.
Eny Kusrini, Fatimah Hashim, Azrina Aziz, Muhamad Fairus Noor Hassim, Anwar Usman, Lee D. Wilson, El-Sayed Negim, Agus Budi Prasetyo   +7 more
doaj   +2 more sources

Screening of the Anti-amoebic Effect of Boric Acid on Acanthamoeba spp. and Its Cytotoxic Activity on Human Neuroblastoma and Keratinocyte Cell Lines

Düzce Tıp Fakültesi Dergisi
Aim: Acanthamoeba spp. infections are rare but may cause severe keratitis. Boric acid (BA) is widely used in ophthalmic solutions because of its buffering and antiseptic properties.
Ömer Erdoğan, Erdogan Malatyali
doaj   +2 more sources

Potential Inhibitors of Human–Naegleria fowleri Interactions: An In Vitro Extracellular Matrix-Based Model [PDF]

Marine Drugs
Primary amoebic meningoencephalitis (PAM) is a rapidly progressive and fulminant disease that affects the central nervous system caused by the free-living amoeba Naegleria fowleri.
Javier Chao-Pellicer, Iñigo Arberas-Jiménez, Ines Sifaoui, Ana R. Díaz-Marrero, José J. Fernández, Melissa Jamerson, José E. Piñero, Jacob Lorenzo-Morales   +7 more
doaj   +2 more sources

The Natural History of Acanthamoeba Keratitis: A Systematic Literature Review [PDF]

Ophthalmology and Therapy
Introduction Acanthamoeba keratitis (AK) was first identified in 1972 and the first patient cured with propamidine was reported in 1985. Treatment outcomes, before the advent of the first effective anti-amoebic treatment, were known to be poor and often ...
Vincenzo Papa, Danielle H. Bodicoat, Angela Arteaga Duarte, John K. G. Dart, Maria De Francesco   +4 more
doaj   +2 more sources

Silver(I)-NHC Complexes as Dual-Action Agents Against Pathogenic <i>Acanthamoeba</i> Trophozoites: Anti-Amoebic and Anti-Adhesion Activities. [PDF]

Int J Mol Sci
A series of six silver(I) complexes, namely bromo(1-benzyl-3-cinnamyl-benzimidazol-2-ylidene)silver (I) (1a), bromo[1-(4-methylbenzyl)-3-cinnamyl-benzimidazol-2-yliden]silver(I) (1b), bromo[1-(3-methoxylbenzyl)-3-cinnamyl-benzimidazol-2-yliden]silver(I) (1c), bromo[1-(3,5-dimethoxy-benzyl)-3-cinnamyl-benzimidazol-2-ylidene]silver(I) (1d), bromo[1 ...
Hkiri S, Şahin N, Akın-Polat Z, Üstün E, Ly BMT, Özdemir İ, Sémeril D.   +6 more
europepmc   +3 more sources

Recent in vitro advances in the ocular antimicrobial agents against Acanthamoeba [PDF]

International Journal for Parasitology: Drugs and Drug Resistance
This review examines the advancements in antimicrobial drug discovery with in vitro assays for Acanthamoeba, highlighting the efficacy of current topical antimicrobial agents.
Chun-Hsien Chen, Jian-Ming Huang, Yu-Jen Wang, Chih-Ming Tsai, Wei-Chen Lin   +4 more
doaj   +2 more sources

Drug repurposing: a dual-mechanism antibiotic combats MRSA and its high resistant phenotypes [PDF]

Frontiers in Cellular and Infection Microbiology
PurposeMethicillin-resistant Staphylococcus aureus (MRSA) is frequently observed in biofilm form, exhibiting significant tolerance, particularly in the context of deep tissue infections such as osteomyelitis.
Pengfei She, Dan Xiao, Dan Xiao, Guanqing Huang, Guanqing Huang, Shaowei Guo, Shaowei Guo, Yiqing Liu, Yiqing Liu, Mengna Li, Mengna Li, Lihua Lu, Lihua Lu, Yelan Hong, Yelan Hong, Yong Wu, Yong Wu   +16 more
doaj   +2 more sources

Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4 [PDF]

International Journal for Parasitology: Drugs and Drug Resistance
Acanthamoebae are opportunistic pathogens causing serious human infections, including granulomatous amoebic encephalitis (GAE) and Acanthamoeba keratitis (AK). The treatment of those infections is limited and difficult to date.
Miloš Lukáč, Martin Pisárčik, Mária Garajová, Julia Walochnik, Daniela Ošustová, Eva Vatrtová, Iryna Bondar, Ferdinand Devínsky, Martin Mrva   +8 more
doaj   +2 more sources

Antimicrobial activity of some isatin-3--thiosemicarbazone complexes [PDF]

Journal of the Serbian Chemical Society, 2008
Isatin-3-thiosemicarbazone complexes with Co(II), Ni(II), Cu(II), Zn(II), Hg(II) and Pd(II) were synthesized and evaluated for their antimicrobial activity against 7 pathogenic bacteria and 4 fungi. The complexes have an enhanced activity compared to the
SANDRA S. KONSTANTINOVIC, BLAGA C. RADOVANOVIC, SOFIJA P. SOVILJ, SVETLANA STANOJEVIC   +3 more
doaj   +3 more sources

Riluzole, a Derivative of Benzothiazole as a Potential Anti-Amoebic Agent against Entamoeba histolytica

Pharmaceuticals, 2023
Amoebiasis is produced by the parasite Entamoeba histolytica; this disease affects millions of people throughout the world who may suffer from amoebic colitis or amoebic liver abscess.
Maritza Velásquez-Torres, José Guadalupe Trujillo-Ferrara, Marycarmen Godínez-Victoria, Rosa Adriana Jarillo-Luna, Víctor Tsutsumi, Virginia Sánchez-Monroy, Araceli Posadas-Mondragón, Roberto Issac Cuevas-Hernández, José Angel Santiago-Cruz, Judith Pacheco-Yépez   +9 more
doaj   +1 more source