Results 41 to 50 of about 294,275 (335)

Treatment of Alzheimer's Disease with Anti-Homocysteic acid Antibody [PDF]

, 2008
Homocysteic acid (HA) may play an important role in Alzhiemer disease (AD) as we previously reported that HA induced accumulation of intraneuronal A[beta]42. In this study, we first analyzed HA levels in a mouse model of AD.
Frank M. LaFerla, Masashi Kitazawa, Nobuyuki Mikoda, Tohru Hasegawa   +3 more
core   +5 more sources

Anxiety-like behavior and anxiolytic treatment in the Rett syndrome natural history study

Journal of Neurodevelopmental Disorders, 2022
Background Rett syndrome (RTT) is a neurodevelopmental disorder most often related to a pathogenic variant in the X-linked MECP2 gene. Internalizing behaviors appear to be common, but standard methods of diagnosing anxiety are not readily applied in this
Caroline B. Buchanan, Jennifer L. Stallworth, Aubin E. Joy, Rebekah E. Dixon, Alexandra E. Scott, Arthur A. Beisang, Timothy A. Benke, Daniel G. Glaze, Richard H. Haas, Peter T. Heydemann, Mary D. Jones, Jane B. Lane, David N. Lieberman, Eric D. Marsh, Jeffrey L. Neul, Sarika U. Peters, Robin C. Ryther, Steve A. Skinner, Shannon M. Standridge, Walter E. Kaufmann, Alan K. Percy   +20 more
doaj   +1 more source

Psychological impact of coronavirus disease 2019 pandemic on patients with rheumatological disorders: A web-based cross-sectional multicentric survey

Indian Journal of Rheumatology, 2021
Background: The coronavirus disease 2019 (COVID-19) pandemic has resulted in uncertainty and negative psychological outcomes for patients with autoimmune rheumatic diseases for several reasons.
G C Yathish, Yogesh Preet Singh, Shiva Prasad, Nagaraj Srinivasulu, Sharath Kumar, R Subramanian, Pramod Chebbi, Vikramraj Jain, Naman Jain, Satish Kumar   +9 more
doaj   +1 more source

Fact-based Agent modeling for Multi-Agent Reinforcement Learning [PDF]

arXiv, 2023
In multi-agent systems, agents need to interact and collaborate with other agents in environments. Agent modeling is crucial to facilitate agent interactions and make adaptive cooperation strategies. However, it is challenging for agents to model the beliefs, behaviors, and intentions of other agents in non-stationary environment where all agent ...
arxiv  

Uso indevido de benzodiazepínicos: um estudo com informantes-chave no município de São Paulo Uso indebido de Benzodiazepínicos: un estudio con informantes-clave en el municipio de São Paulo Misuse of benzodiazepines: a study among key informants in São Paulo city

Revista Latino-Americana de Enfermagem, 2005
Este estudo teve por objetivo compreender a prática de prescrição, dispensação e uso prolongado de benzodiazepínicos, a partir da visão de profissionais de saúde e de usuários crônicos dessas substâncias.
Paula Orlandi, Ana Regina Noto
doaj   +1 more source

Phenanthroindolizidine Alkaloids Secondary Metabolites Diversity in Medicinally Viable Plants of the Genus Tylophora

Plants, 2023
Plants of the genus Tylophora have commonly been used in traditional medicine in various communities, especially in the tropical and subtropical regions of climatic zones.
Ehab M. Mostafa, Arafa Musa, Hamdoon A. Mohammed, Abdulaziz Ibrahim Alzarea, Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Ahmed Ismail, Ameeduzzafar Zafar, Mohammed Elmowafy, Samy Selim, Riaz A. Khan   +10 more
doaj   +1 more source

Co-Occurrence and Characteristics of Patients With Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia : Results From a UK National Register [PDF]

, 2017
The British Society for Rheumatology (BSR) Biologics Register in Ankylosing Spondylitis is funded by the BSR and they have receive funds for this from Pfizer, AbbVie and UCB.
Atzeni, Fabiola, Barnish, Maxwell S, Haywood, Kirstie L, Jones, Gareth T, MacFarlane, Gary J, Martin, Kathryn R, Packham, Jonathan, Pathan, Ejaz, Siebert, Stefan   +8 more
core   +2 more sources

Thiophene derivative inflicts cytotoxicity via an intrinsic apoptotic pathway on human acute lymphoblastic leukemia cells.

PLoS ONE, 2023
In an effort to identify novel anti-cancer agents, we employed a well-established High Throughput Screening (HTS) assay to assess the cytotoxic effect of compounds within the ChemBridge DIVERSet Library on a lymphoma cell line.
Risa Mia Swain, Anahi Sanchez, Denisse A Gutierrez, Armando Varela-Ramirez, Renato J Aguilera   +4 more
doaj   +1 more source

How and why systemic inflammation worsens quality of life in patients with advanced cancer [PDF]

, 2017
Introduction: The presence of an innate host systemic inflammatory response has been reported to be a negative prognostic factor in a wide group of solid tumour types in both the operable and advanced setting, both local and distant.
Dolan, Ross D., Horgan, Paul G., McMillan, Donald C., McSorley, Stephen T., Roxburgh, Campbell S.D.   +4 more
core   +1 more source

Prevalence and factors associated with the use of benzodiazepines among teachers in Espírito Santo: a cross-sectional study [PDF]

Revista Brasileira de Epidemiologia
Objective: This study analyzed the prevalence and associated factors of benzodiazepine use among teachers in municipalities of Espírito Santo, Brazil, in 2024.
Yohan Cancilheri Mazzini, Bruna Lopes Antonucci, Guilherme Rocha Pereira, Walleri Christini Torelli Reis, Kérilin Stancine Santos Rocha, André Faro, Dyego Carlos Souza Anacleto de Araújo   +6 more
doaj   +1 more source