Results 81 to 90 of about 592,213 (353)

AB1040 CHARACTERIZATION OF ANXIETY AND DEPRESSION AND THEIR IMPACT ON DISEASE ACTIVITY, FATIGUE AND QUALITY OF LIFE IN SPONDYLARTHRITIS PATIENTS TREATED WITH ANTI-TUMOR NECROSIS FACTOR ALPHA AGENTS [PDF]

, 2023
D. Santos Oliveira, A. Martins, Rafaela Nicolau, Carlos Vaz, T. Martins-Rocha, A. Bernardo, M. Bernardes, L. Costa   +7 more
openalex   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]

, 2016
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina, De Santis, Stefano, Fulvi, Alberto, Giovannoni, Daniele, Marcassa, Claudio, Migliorino, Maria Rita, Ricciardi, Serena   +6 more
core   +2 more sources

Anti-vascular endothelial growth factor in neovascular age-related macular degeneration – a systematic review of the impact of anti-VEGF on patient outcomes and healthcare systems

BMC Ophthalmology, 2020
Background Systematically review the evidence describing the impact of anti–vascular endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular degeneration (nAMD) patient outcomes and healthcare resource utilization.
Robert P. Finger, Vincent Daien, Bora M. Eldem, James S. Talks, Jean-Francois Korobelnik, Paul Mitchell, Taiji Sakamoto, Tien Yin Wong, Krystallia Pantiri, Joao Carrasco   +9 more
doaj   +1 more source

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Health related effects of wheat varieties [PDF]

, 2020
Summarises the different effects wheat digestion has on human ...
Borgen, Anders
core  

Research Progress on Idebenone in Neurodegenerative Diseases

AGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang, Yanhong Ren, Xiaoran Zhu, Tianhao Liu, Rundong Han, Yuqing Fang, Zhangning Zhao, Fei Mao, Yalin Wang, Xian Li, Xiuhua Li   +10 more
wiley   +1 more source

The Defeasibility of Knowledge-How [PDF]

, 2017
Reductive intellectualists (e.g., Stanley & Williamson 2001; Stanley 2011a; 2011b; Brogaard 2008; 2009; 2011) hold that knowledge-how is a kind of knowledge-that. If this thesis is correct, then we should expect the defeasibility conditions for knowledge-
Alston, Bengson, Bergmann, Bergmann, Carter, Carter, Carter, Carter, Carter, Carter, Cath, Cath, Choi, Choi, Chrisman, Dreyfus, Engel, Glick, Goldberg, Goldman, Greco, Greco, Hawley, Hornsby, Lackey, Lackey, Lackey, Maier, Mele, Navarro, Nöe, Papineau, Pavese, Pavese, Pollock, Pollock, Poston, Poston, Pritchard, Sacks, Schiffer, Searle, Shah, Shah, Snowdon, Sosa, Sosa, Sosa, Stanley, Stanley, Stanley, Stinear, Sudduth, Wedgwood, Wilson, Wittgenstein   +55 more
core   +3 more sources

Delivering a family‐based child mental health promotion program among two resettled refugee communities during the COVID‐19 pandemic: Lessons learned in a hybrid type II implementation‐effectiveness randomized controlled trial

American Journal of Community Psychology, EarlyView.
Abstract Background Resettled refugee families face elevated mental health risks, compounded by structural and cultural barriers. The Family Strengthening Intervention for Resettlement (FSIR), co‐developed with resettled refugee communities, aims to improve family functioning and child mental health.
Euijin Jung, Candace Black, Matias Placencio‐Castro, Lila Chamlagai, Rilwan Osman, Morgan Hoffman, William Beardslee, Theresa S. Betancourt   +7 more
wiley   +1 more source