Results 41 to 50 of about 30,394 (309)

Molecular and immunomodulatory actions of new antiasthmatic agents: Exploring the diversity of biologics in Th2 endotype asthma

open access: yesPharmacological Research, 2022
Asthma is a major respiratory disorder characterised by chronic inflammation and airway remodelling. It affects about 1–8% of the global population and is responsible for over 461,000 deaths annually.
Emmanuel Oshiogwe Okwuofu   +3 more
doaj  

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Development of bronchial sensitization to inhalant allergens in occupational asthma patients

open access: yesAllergology International, 1997
In cases of occupational asthma due to reactive chemicals, an appreciable number of patients have persistent asthmatic symptoms and airway inflammation even after several years' avoidance of the cause agents. A case of late respiratory systemic syndrome (
Hae-sim Park, Dong-ho Nahm
doaj   +1 more source

CpG oligodeoxynucleotides attenuate RORγt-mediated Th17 response by restoring histone deacetylase-2 in cigarette smoke-exposure asthma

open access: yesCell & Bioscience, 2021
Background Cigarette smoke (CS) exposure increases corticosteroid insensitive asthma related to increased Th17 phenotype, and new treatment strategies are needed for CS-associated asthma.
Hongtao Li   +8 more
doaj   +1 more source

Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]

open access: yes, 2011
Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams   +207 more
core   +1 more source

A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED [PDF]

open access: yes, 2016
RATIONALE AND OBJECTIVES: Asthma is a heterogeneous disease driven by diverse immunologic and inflammatory mechanisms. We used transcriptomic profiling of airway tissues to help define asthma phenotypes. METHODS: The transcriptome from bronchial biopsies
Adcock, IM   +28 more
core   +4 more sources

Rediscovering the Therapeutic Potential of Agarwood in the Management of Chronic Inflammatory Diseases

open access: yesMolecules, 2022
The inflammatory response is a central aspect of the human immune system that acts as a defense mechanism to protect the body against infections and injuries.
Juman Mohammed Rasmi Alamil   +15 more
doaj   +1 more source

Nonsteroidal Anti-Inflammatory Agents in the Treatment of Asthma in Children

open access: yesCanadian Respiratory Journal, 1995
The increasing scientific information clearly demonstrates the important role of inflammation in asthma. This evidence has led physicians to focus their treatment on the elimination of inflammation instead of working solely against bronchoconstriction ...
Pierre Gaudreault
doaj   +1 more source

Local anaesthetic medication for the treatment of asthma

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for ...
Rodrigo A Siqueira   +5 more
doaj   +1 more source

Asthma and COVID-19: a dangerous liaison?

open access: yesAsthma Research and Practice, 2021
The coronavirus disease 2019 (COVID-19) pandemic, caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), provoked the most striking international public health crisis of our time. COVID-19 can cause a range of breathing problems,
Carlo Lombardi   +5 more
doaj   +1 more source

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