Results 101 to 110 of about 3,484,912 (268)

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Explore the antibiofilm ability of Ampelopsis cantoniensis extract against Staphylococcus aureus via experimental and computional approaches

Tạp chí Khoa học và Công nghệ
Our study aimed to evaluate the anti-biofilm activity of the crude ethanolic extract of Ampelopsis cantoniensis against Staphylococcus aureus (S. aureus) isolated from clinical specimens.
Van Ngo Thai Bich, Y Ngo Huynh Thien, Chau Thi Bui, Trinh Pham Thi Doan, Phu Tran Vinh Pham   +4 more
doaj   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Prospects for Anti-Biofilm Pharmaceuticals

Pharmaceuticals, 2015
This commentary highlights several avenues currently being pursued in research labs to the development of new anti-biofilm pharmaceuticals. There is a real need for alternative therapeutic modalities for treating the persistent infections that sometimes ...
Philip S. Stewart
doaj   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

Promising Antibiofilm Agents: Recent Breakthrough against Biofilm Producing Methicillin-Resistant Staphylococcus aureus

, 2020
Multidrug resistant (MDR) methicillin-resistant Staphylococcus aureus (MRSA) is a superbug pathogen that causes serious diseases. One of the main reasons for the lack of the effectiveness of antibiotic therapy against infections caused by this resistant ...
Wael A. H. Hegazy, Nabil A. Alhakamy, Wesam H. Abdulaal, El-sayed Y. El-Naenaeey, Mahmoud M. Bendary, Marwa I. Abd El-Hamid, Majed S. Nassar, Toka M kandeel, Rasha A. Mosbah, Muhammed A. Bakhrebah   +9 more
core   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Anti-biofilm activity as a health issue

Frontiers in Microbiology, 2016
The formation and persistence of surface-attached microbial communities, known as biofilms, are responsible for 75% of human microbial infections (National Institutes of Health).
Sylvie eMiquel, Rosyne eLagrafeuille, Bertrand eSouweine, Bertrand eSouweine, Christiane eForestier   +4 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source