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Detection to Disruption: A Comprehensive Review of Bacterial Biofilms and Therapeutic Advances. [PDF]
Maroju PA +8 more
europepmc +1 more source
Biofilm-Forming Methicillin-Resistant Staphylococcus aureus: A Comprehensive Phenotypic and Genotypic Review. [PDF]
Bhujugade SR, Patil HV, Patil SR.
europepmc +1 more source
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance
Biofilm formation significantly contributes to microbial survival in hostile environments and it is currently considered a key virulence factor for pathogens responsible for serious chronic infections. In the last decade many efforts have been made to identify new agents able to modulate bacterial biofilm life cycle, and many compounds have shown ...
Barbara Parrino +2 more
exaly +4 more sources
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Actinobacteria—a promising natural source of anti-biofilm agents
International Microbiology, 2019A biofilm is a community of microorganisms attached to a surface and embedded in a matrix of extracellular polymeric substances. Biofilms confer resistance towards conventional antibiotic treatments; thus, there is an urgent need for newer and more effective antimicrobial agents that can act against these biofilms.
Adzzie-Shazleen Azman +2 more
exaly +3 more sources
Quorum Sensing Inhibitors as Anti-Biofilm Agents
Current Pharmaceutical Design, 2014Biofilms are microbial sessile communities characterized by cells that are attached to a substratum or interface or to each other, are embedded in a self-produced matrix of extracellular polymeric substances and exhibit an altered phenotype compared to planktonic cells.
Gilles, Brackman, Tom, Coenye
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Synthetic non-toxic anti-biofilm agents as a strategy in combating bacterial resistance
European Journal of Medicinal Chemistry, 2023The tremendous increase in the bacterial resistance to the available antibiotics is a serious problem for the treatment of various infections. Biofilm formation in bacteria significantly contributes to the bacterial survival in host cells, and is considered as an crucial factor, responsible for bacterial resistance.
Rasha M Hassan +1 more
exaly +3 more sources

