Results 101 to 110 of about 131,343 (218)
Proteomics in drug hypersensitivity [PDF]
, 2016 21 p.-4 fig.-1 tab.Drug hypersensitivity reactions result from the activation of the immune system by drugs or their metabolites. The clinical presentations of drug hypersensitivity can range from relatively mild local manifestations to severe systemic ...
Aldini, Giancarlo +4 more
core +1 more source
THU0090 Prevalence and clinical phenotype of anti-carbamylated protein antibodies in palindromic rheumatism [PDF]
Annals of the Rheumatic Diseases, 2018 Background Anti-carbamylated protein antibodies (anti-CarP) are a newly-identified antibody family present in the sera of rheumatoid arthritis (RA) patients whose specificity is close to that of ACPA but whose sensitivity is lower. Palindromic rheumatism (PR) is an intermittent form of arthritis that may progress to RA.
R. Castellanos-Moreira +13 more
openaire +1 more source
Acta Physiologica, Volume 241, Issue 5, May 2025.The source of the GGCX protein structure is uniprot, (image in the upper left of the graphical): this is the weblink: https://www.uniprot.org/uniprotkb/P38435/entry Abstract Aim Vascular calcification contributes to morbidity and mortality in aging and is accelerated in diabetes and in chronic kidney disease. Matrix Gla Protein is a potent inhibitor of
Nadine Kaesler +12 more
wiley +1 more source
Anti-Carbamylated Protein Antibody Test Accuracy In Some Iraqi Patients With Rheumatoid Arthritis
Medical Science Journal for Advance Research, 2022 Background: Rheumatoid arthritis is a persistent, immune-mediated disorder that causes pain, edema, and inflammation in the joints. A genetic history that is high in risk, when paired with genomic markers and environmental exposures, triggers a series of actions that not only results in synovitis and arthritis, but also affects a great number of organs
openaire +1 more source
Journal of Periodontology, Volume 95, Issue 10, Page 929-941, October 2024.Abstract Background Malondialdehyde–acetaldehyde (MAA) adducts lead to generation of anti‐MAA autoantibodies and have been independently identified in inflamed periodontal and rheumatoid arthritis (RA) tissues. This study evaluates serum samples from RA cases and osteoarthritis (OA) controls to quantify associations between periodontal clinical ...
Joyce A. Lee +5 more
wiley +1 more source
The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching [PDF]
Rheumatology, 2018 To better understand the contribution of autoantibodies in RA and the biology of their responses, we evaluated the avidity of the anti-carbamylated protein (anti-CarP) antibody response.The avidity of anti-CarP antibody, ACPA and anti-tetanus toxoid IgG were determined using elution assays. Anti-CarP IgG avidity was measured in sera of 107 RA patients,
van Delft +8 more
openaire +3 more sources
ACR Open Rheumatology, Volume 6, Issue 9, Page 587-597, September 2024.Objective Rheumatoid arthritis (RA) has a “pre‐RA” period in which multiple autoantibodies, including antibodies to citrullinated (cit) proteins (ACPA), rheumatoid factor (RF), anti–peptidyl arginine deiminase (anti‐PAD), among others, have been described; however, few studies have tested all autoantibodies in a single pre‐RA cohort. This study aims to
Salina H. Goff +10 more
wiley +1 more source
Journal of Medical Virology, Volume 96, Issue 8, August 2024.Abstract Understanding the pathophysiology of long COVID is one of the most intriguing challenges confronting contemporary medicine. Despite observations recently made in the relevant molecular, cellular, and physiological domains, it is still difficult to say whether the post‐acute sequelae of COVID‐19 directly correspond to the consequences of severe
Alain R. Thierry, Dominique Salmon
wiley +1 more source
Anti-citrullinated protein antibody positive rheumatoid arthritis is primarily determined by rheumatoid factor titre and the shared epitope rather than smoking per se. [PDF]
, 2017 OBJECTIVE: To analyse the relationship between rheumatoid factor (RF) titre, smoking and HLA-DRB1 alleles coding a "shared epitope" (SE) in relation to anti-citrullinated protein antibody (ACPA) positivity in rheumatoid arthritis (RA).
Hutchinson, D, Mattey, D, Murphy, D
core +1 more source
Endothelial dysfunction: molecular mechanisms and clinical implications
MedComm, Volume 5, Issue 8, August 2024.Endothelial dysfunction is commonly linked to various disease states resulting from an imbalance in the production of vasodilators and vasoconstrictors, among other factors. Human diseases associated with endothelial dysfunction include atherosclerosis, diabetes, metabolic syndrome, neurodegenerative diseases, chronic kidney disease, hypertension ...
Xia Wang, Ben He
wiley +1 more source