Results 101 to 110 of about 5,298,732 (170)

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

Arthritis Research & Therapy, 2018
Background The autoantibody profile of seropositive rheumatoid arthritis (RA) is very diverse and consists of various isotypes and antibodies to multiple post-translational modifications. It is yet unknown whether this varying breadth of the autoantibody
Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

Anti-carbamylated protein antibodies in patients with systemic sclerosis: an intriguing association with skin involvement

, 2017
Background Systemic sclerosis (SSc), one of the most complex connective tissue disease, is characterized by three pathogenic events namely, vascular damage, autoimmunity and fibroblast activation, leading to a widespread fibrosis of skin and internal ...
F. Perosa, M. Prete, Corrado, A, S Vettori2, G Valentini, A. corrado, Valentini, G, Prete, M, S Vettori, A Corrado, F. P. Cantatore, Vettori, S, FP Cantatore, Favoino, E, E. Favoino, Cantatore, FP, M Prete, F Perosa, G. Valentini, S. Vettori, Perosa, F, E Favoino   +21 more
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Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients

BMC Musculoskeletal Disorders, 2017
Background Rheumatoid arthritis (RA) patients carry a high risk of cardiovascular morbidity and mortality. The excess of cardiovascular disease cannot be entirely explained by traditional risk factors and the immune system contributes to the development ...
Francesca Romana Spinelli, Arbi Pecani, Francesco Ciciarello, Tania Colasanti, Manuela Di Franco, Francesca Miranda, Fabrizio Conti, Guido Valesini, Cristiano Alessandri   +8 more
doaj   +1 more source

Evaluation of anti-citrullinated and anti-carbamylated antibodies in mexicans with rheumatoid arthritis and at-risk individuals

Revista de Investigación Clínica
Background: Rheumatoid arthritis (RA) diagnosis is a challenge in the initial phases of the disease when clinical symptoms are only starting to develop.
Edgar E. Lara-Ramírez, Betzaida Cuevas-Córdoba, Diana Olguín-Calderon, Yadira Bastian, César Ramos-Remus, José D. Castillo-Ortiz, Martín Zapata-Zúñiga, Jesús Núñez-Contreras, Leendert A. Trouw, José A. Enciso-Moreno, Julio E. Castañeda-Delgado   +10 more
doaj   +1 more source

Determination of islet cell antibodies using an ELISA system with a preparation of rat insulinoma (RIN A2) cells [PDF]

, 1989
An enzyme-linked immunosorbent assay (ELISA) was established for the detection of islet cell antibodies in human sera. The antigen was prepared from rat insulinoma (RIN A2) cells.
Seißler, Jochen, Hedderich, U., Specker, M., Pfeiffer, Ernst Friedrich, Böhm, Bernhard Otto, Scherbaum, Werner A.   +5 more
core   +1 more source

Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort study

RMD Open
Objectives To evaluate the potential of clinical factors, ultrasound findings, serum autoantibodies, and serum cytokine and chemokine profiles as predictors of clinical outcomes in rheumatoid arthritis (RA).Patients and methods We included 200 patients ...
Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada   +28 more
doaj   +1 more source

Unravelling the anti-carbamylated protein antibody response in rheumatoid arthritis [PDF]

, 2019
Although quite some data is available on anti-CarP antibodies, several questions remain unanswered, including the reproducibility of the clinical data on anti-CarP antibodies, such as their presence before disease onset and association with
Verheul, M.K.
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An investigation of the molecular basis of interactions between human monoclonal antibodies and antigens that are clinically relevant in systemic lupus erythematosus and the Antiphospholipid Syndrome. [PDF]

, 2007
Autontibodies to a wide variety of antigens are associated with systemic lupus erythematosus (SLE) and the Antiphospholipid Syndrome (APS).
Lambrianides, A.
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Targeted expression of the anti-HIV microbicide lectin griffithsin in maize and tobacco [PDF]

, 2013
Includes abstract.Includes bibliographical references.Plants are emerging as cost friendly alternative production systems for a variety of pharmaceuticals. Numerous therapeutic proteins have been produced in plant systems (Giddings et al., 2000; Ma et al.
Stark, Hester Catharina (Therese)
core   +1 more source

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

, 2021
ObjectiveAntibodies targeting post-translationally modified proteins, such as anti-carbamylated protein antibodies (anti-CarP antibodies) are present in sera of rheumatoid arthritis (RA) patients.
Veelen, P.A. van, Verheul, M.K., Bomer, N., Meulenbelt, I., Trouw, L.A., Cordfunke, R.A., Stoeken-Rijsbergen, G., Ioan-Facsinay, A., Ru, A. de, Janssen, G.M.C., Levarht, E.W.N., Kwekkeboom, J.C., Drijfhout, J.W., Toes, R.E.M.   +13 more
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