Results 21 to 30 of about 809 (171)
Immunity, Inflammation and Disease, Volume 11, Issue 12, December 2023., 2023 Abstract Background Autoimmune diseases (AD) are severe pathophysiological ailments that are stimulated by an exaggerated immunogenic response towards self‐antigens, which can cause systemic or site‐specific organ damage. An array of complex genetic and epigenetic facets majorly contributes to the progression of AD, thus providing significant insight ...
Sagnik Nag +15 more
wiley +1 more source
Therapeutic Advances in Musculoskeletal Disease, 2021 Background: Anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are key factors in the American College of Rheumatology/European League Against Rheumatism rheumatoid arthritis (RA) classification criteria markers.
Bogdan Kolarz +4 more
doaj +1 more source
Immunity, Inflammation and Disease, Volume 11, Issue 6, June 2023., 2023 Linc00324 is significantly increased in peripheral blood mononuclear cells of rheumatoid arthritis (RA). Linc00324 is preferentially expressed in CD4+ T cells, and promots CD4+ T cells proliferation and MIP‐1α secretion. Linc00324 may contribute to RA pathogenesis through NF‐κB signaling by targeting miR‐10a‐5p.
Binbin Xie +7 more
wiley +1 more source
MedComm, Volume 4, Issue 3, June 2023., 2023 The reversible and irreversible protein posttranslational modifications, such as acetylation, methylation, phosphorylation, ubiquitination, glycosylation, SUMOylation, and redox modifications, are essential regulators in organisms and cells. This work systematically summarizes the features, regulatory mechanisms, substrates, functions, and related ...
Qian Zhong +10 more
wiley +1 more source
Arthritis Care &Research, Volume 75, Issue 4, Page 936-946, April 2023., 2023 Objective Native American (NA) populations have higher rates of rheumatic disease and present with overlapping disease symptoms and nontraditional serologic features, thus presenting an urgent need for better biomarkers in NA diagnostics. This study used a machine learning approach to identify immune signatures that more effectively stratify NA ...
Samantha Slight‐Webb +11 more
wiley +1 more source
FRI0040 Characterization of anti-carbamylated synovial protein antibodies (ANTI-CARPS) in rheumatoid arthritis patients [PDF]
Annals of the Rheumatic Diseases, 2017 Background Anti-carbamylated protein antibodies (anti-CarP) are a new type of autoantibodies specific of patients with RA. Reactivity has generally been tested with in vitro carbamylated proteins from fetal calf serum (FCS) as anti-CarPF. It is likely that other sources of antigens could be more suitable than FCS unless the reactivity of the ...
C Regueiro +6 more
openaire +1 more source
ACR Open Rheumatology, Volume 5, Issue 4, Page 201-226, April 2023., 2023 Background Biomarkers have been proposed as tools to aid in the identification and prognostication of interstitial lung disease (ILD) in rheumatoid arthritis (RA). We performed a systematic review of studies evaluating peripheral blood biomarkers and their association with RA‐ILD and its prognosis.
Daniel Van Kalsbeek +10 more
wiley +1 more source
Studying the Link between Rheumatoid Arthritis and Gut Dysbiosis: A Mini Review
Advanced Gut &Microbiome Research, Volume 2022, Issue 1, 2022., 2022 Rheumatoid arthritis (RA) is an autoimmune disease that affects the joints and may lead to disability. Recent advances have allowed us to study the human gut microbiota in great details. Numerous studies have shown that changes in gut microbiota may be playing a critical role in the pathogenesis of RA.
Mohammad Zulqurnain Haider, Jiong Yu
wiley +1 more source
Crosstalk between B cells and neutrophils in rheumatoid arthritis
Immunology, Volume 164, Issue 4, Page 689-700, December 2021., 2021 This article reviews insights into cross‐talk between B cells and neutrophils in seropositive rheumatoid arthritis and its pathogenesis. Abstract Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease without known cure that primarily affects synovial joints. RA has a prevalence of approximately 1% of the population worldwide.
Utsa Karmakar, Sonja Vermeren
wiley +1 more source
Association Between Bone Mineral Density and Autoantibodies in Patients With Rheumatoid Arthritis
Arthritis &Rheumatology, Volume 73, Issue 6, Page 921-930, June 2021., 2021 Objective Autoantibodies, such as anti–citrullinated protein antibodies (ACPAs), have been described as inducing bone loss in rheumatoid arthritis (RA), which can also be reflected by bone mineral density (BMD). We therefore examined the association between osteoporosis and autoantibodies in two independent RA cohorts. Methods Dual x‐ray absorptiometry
Josephine A. M. P. Amkreutz +12 more
wiley +1 more source