Results 31 to 40 of about 809 (171)

A5.4 Anti Carbamylated Protein Antibodies (Anti-CarP) Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis [PDF]

Annals of the Rheumatic Diseases, 2013
Background/Objective Recently, we discovered a new auto- antibody system in rheumatoid arthritis (RA): anti carbamylated protein antibodies (anti-CarP). These antibodies have additional prognostic value in predicting joint destruction when compared to anti-citrullinated protein antibodies (ACPA).
Jing Shi, Lotte A van de Stadt, EW Nivine Levarht, Tom WJ Huizinga, René EM Toes, Leendert A Trouw, Dirkjan van Schaardenburg   +6 more
openaire   +1 more source

Do anti-carbamylated protein antibodies in rheumatoid arthritis reflect local and systemic osteoporosis? A study of osteoprotegrin and receptor activator for nuclear factor kappa B ligand and radiological assessment

Egyptian Rheumatology and Rehabilitation, 2021
Background One of the most important and dangerous complications of rheumatoid arthritis (RA) is bone loss, which manifested by erosions and juxta-articular or systemic bone loss.
Manal Shawky Hussein, Rasha Ahmed Gaber, Hala Mostafa Elsabagh, Elsayed Mohamed Rageh   +3 more
doaj   +1 more source

Diagnostic value and clinical significance of anti-carbamylated protein (anti-CarP) antibodies in Egyptian patients with rheumatoid arthritis

The Egyptian Rheumatologist, 2020
Abstract Aim of the work The study was performed to assess the diagnostic potential of anti-carbamylated proteins (anti-CarP) antibodies in Egyptian patients with RA and their relation to clinical manifestations, laboratory findings and radiological damage.
Samar R. Mohamed, Nanis O. Neseem, Shereen S. Metwally, Basma A. El-Kady   +3 more
openaire   +1 more source

Effect of Etanercept on anti-carbamylated protein antibodies in patients with rheumatoid arthritis [PDF]

, 2015
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e.
Alessandri, Cristiano, Ceccarelli, Fulvia, Conti, Fabrizio, Pecani, Arbi, Spinelli, FRANCESCA ROMANA   +4 more
core   +1 more source

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]

, 2016
Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano, Barbati, Cristiana, Ceccarelli, Fulvia, Colasanti, Tania, Conti, Fabrizio, DI FRANCO, Manuela, Mancini, Riccardo, Morello, Francesca, Pecani, Arbi, Pendolino, Monica, Priori, Roberta, Riccieri, Valeria, Sabatinelli, Danilo, Spinelli, FRANCESCA ROMANA, Truglia, Simona, Valesini, Guido, Vomero, Marta   +16 more
core   +1 more source

Arthritis autoantibodies in individuals without rheumatoid arthritis:follow-up data from a Dutch population-based cohort (Lifelines) [PDF]

, 2021
Objectives. To assess whether the presence of arthritis autoantibodies alongside IgG ACPA predicts clinically suspect arthralgia in ACPA-positive subjects without RA. Methods.
Arends, Suzanne, Brouwer, Elisabeth, de Smit, Menke J, Eman Abdulle, Amaal, Raveling-Eelsing, Elisabeth, Roozendaal, Caroline, Toes, Rene E M, Trouw, Leendert A, van Delft, Myrthe A M, Vissink, Arjan, Westra, Johanna   +10 more
core   +1 more source

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis:Results from the Norfolk Arthritis Register [PDF]

, 2015
Objectives: Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of this study was to investigate their association with long-term outcomes of disability
Aletaha, Alexander J MacGregor, Anne Barton, Arend, Brink, Burgers, Burska, De, Deborah PM Symmons, Gan, Hecht, Humphreys, Humphreys, Humphreys, Jennifer H Humphreys, Jung, Kosinski, Leendert A Trouw, Marije K Verheul, Mark Lunt, Montes, Nielen, Pope, Quinn, Rene EM Toes, Shi, Shi, Shi, Shidara, Sokolove, Suzanne MM Verstappen, Symmons, van der Helm-van Mil, van der Linden, Wiles, Wolfe, Yee   +36 more
core   +1 more source

Anti-carbamylated protein and peptide antibodies as potential inflammatory joint biomarkers in the relatives of rheumatoid arthritis patients [PDF]

, 2020
*Q3Objective: Antibodies against carbamylated proteins/peptide (CarP) have been associated with severity in rheumatoid arthritis (RA) patients. However, their role in risk groups, specific targets and relation with periodontal disease (PD) is uncertain
Bautista-Molano, Wilson, Bello-Gualtero, Juan-Manuel, Chila-Moreno, Lorena, Ramos-Casallas, Alejandro, Rodríguez Camacho, Luz-Stella, Romero-Sánchez, Consuelo   +5 more
core   +1 more source

Added value of multiple autoantibody testing for predicting progression to inflammatory arthritis in at-risk individuals

RMD Open, 2022
Background Predicting progression to clinical arthritis in individuals at-risk of developing rheumatoid arthritis is a prerequisite to developing stratification groups for prevention strategies. Selecting accurate predictive criteria is the critical step
Paul Emery, K Mankia, Laurence Duquenne, Farag Shuweihdi, L A Trouw, Frederique Ponchel, Diane Corscadden, Xuanxiao Xie   +7 more
doaj   +1 more source

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus [PDF]

, 2018
Background: The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Alessandri, Cristiano, Ceccarelli, Fulvia, Cipriano, Enrica, Colasanti, Tania, Conti, Fabrizio, Mancini, Riccardo, Massaro, Laura, Natalucci, Francesco, Pendolino, Monica, Perricone, Carlo, Spinelli, Francesca Romana, Valesini, Guido   +11 more
core   +1 more source