Results 51 to 60 of about 809 (171)

Does the course of disease influence the development of fatigue in rheumatoid arthritis patients? [PDF]

, 2021
Publisher Copyright: © 2021 Sciendo. All rights reserved.Patients with rheumatoid arthritis (RA) typically have many permanently inflamed joints. The inflammation inside the body can lead to general physical weakness, exhaustion, and drowsiness.
Grāvelsiņa, Sabīne, Kadiša, Anda, Lejnieks, Aivars, Murovska, Modra, Nora-Krūkle, Zaiga, Sokolovska, Lība, Svirskis, Šimons, Vecvagare, Katrīne   +7 more
core   +2 more sources

Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology

Immunological Reviews, Volume 294, Issue 1, Page 148-163, March 2020., 2020
Abstract Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly expanded our understanding of the disease. The best‐known autoantibodies in RA—rheumatoid factor (RF) and anti‐citrullinated protein antibodies (ACPA)—are present
Mikhail Volkov, Karin Anna van Schie, Diane van der Woude   +2 more
wiley   +1 more source

Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications

Arthritis Research & Therapy, 2021
Background Besides anti-citrullinated protein antibodies (ACPA), rheumatoid arthritis patients (RA) often display autoantibody reactivities against other post-translationally modified (PTM) proteins, more specifically carbamylated and acetylated proteins.
M. Volkov, A. S. B. Kampstra, K. A. van Schie, A. Kawakami, M. Tamai, S. Kawashiri, T. Maeda, T. W. J. Huizinga, R. E. M. Toes, D. van der Woude   +9 more
doaj   +1 more source

Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium [PDF]

, 2022
Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis.
Atzeni, Fabiola, Cantatore, Francesco Paolo, Caporali, Roberto, Cassone, Giulia, Cauli, Alberto, Ceccarelli, Fulvia, Conti, Fabrizio, Favalli, Ennio Giulio, Ferraccioli, Gian Franco, Govoni, Marcello, Gremese, Elisa, Iannone, Florenzo, Lapadula, Giovanni, Olivieri, Giulio, Piga, Matteo, Sebastiani, Marco   +15 more
core   +3 more sources

Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Arthritis Research & Therapy, 2020
Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using anti-cyclic ...
Evan Reed, Anna Karin Hedström, Monika Hansson, Linda Mathsson-Alm, Boel Brynedal, Saedis Saevarsdottir, Martin Cornillet, Per-Johan Jakobsson, Rikard Holmdahl, Karl Skriner, Guy Serre, Lars Alfredsson, Johan Rönnelid, Karin Lundberg   +13 more
doaj   +1 more source

Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production [PDF]

, 2017
BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual’s life.
Ana L. Alemán-Navarro, Cesar Ramos-Remus, David Santiago-Algarra, Diana Olguín-Calderón, Jose A. Enciso-Moreno, Jose D. Castillo-Ortiz, Julio E. Castañeda-Delgado, Leendert A. Trouw, Leonor Enciso-Moreno, Noe Macias-Segura, Pedro Martínez-Tejada, Yadira Bastián-Hernandez, Yolanda Garcia-De Lira   +12 more
core   +1 more source

Value of Measuring Anti-Carbamylated Protein Antibodies for Classification on Early Arthritis Patients

Scientific Reports, 2017
Classification of patients with rheumatoid arthritis (RA) as quickly as possible improves their prognosis. This reason motivates specially dedicated early arthritis (EA) clinics.
Cristina Regueiro, Laura Nuño, Ana M. Ortiz, Diana Peiteado, Alejandro Villalba, Dora Pascual-Salcedo, Ana Martínez-Feito, Isidoro González-Alvaro, Alejandro Balsa, Antonio González   +9 more
doaj   +1 more source

Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]

, 2019
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio, Di Franco, Manuela, Guzzo, Maria Paola, Iannuccelli, Cristina, Lucchino, Bruno, Spinelli, Francesca Romani   +5 more
core   +1 more source

Anti-carbamylated protein antibody isotype pattern differs between palindromic rheumatism and rheumatoid arthritis

Therapeutic Advances in Musculoskeletal Disease, 2020
Background: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA).
Raul Castellanos-Moreira, Sebastian C. Rodriguez-Garcia, Sonia Cabrera-Villalba, María José Gomara, Georgina Salvador, Virginia Ruiz-Esquide, Julio Ramirez, Jose Inciarte-Mundo, Rosa Morla, Cristina Garcia-Moreno, Andrea Cuervo, Jose A. Gómez-Puerta, Juan D. Cañete, Isabel Haro, Raimon Sanmarti   +14 more
doaj   +1 more source

Improved diagnosis of rheumatoid arthritis using an artificial neural network

Scientific Reports, 2022
Rheumatoid arthritis (RA) is chronic systemic disease that can cause joint damage, disability and destructive polyarthritis. Current diagnosis of RA is based on a combination of clinical and laboratory features.
Linlu Bai, Yuan Zhang, Pan Wang, Xiaojun Zhu, Jing-Wei Xiong, Liyan Cui   +5 more
doaj   +1 more source