Results 21 to 30 of about 10,355 (194)

New laboratory biomarkers of rheumatoid arthritis

Научно-практическая ревматология, 2021
The review presents data on new biomarkers for the diagnosis of rheumatoid arthritis, considers the diagnostic parameters of antibodies to carbamylated proteins, antibodies to peptidyl arginine deaminase, antibodies to homocysteinylated α1-antitrypsin ...
D. A. Dibrov
doaj   +1 more source

THU0139 IS ADDING ANTI-CARP OR ANTI-PADI4 BENEFICIAL FOR DIAGNOSIS OF RHEUMATOID ARTHRITIS? [PDF]

Annals of the Rheumatic Diseases, 2019
Background Post-translatory modification (PTM), such as protein citrullination or homocitrullination (carbamylation) are key issues for the development of RA. There are known more than 300 PTMs. Some of them such as homocitrullination, are of chemical origin, but most of them (over 200) are of enzymatic origin.
Bogdan Kolarz, Magdalena Dryglewska, Marek Ciesla, Maria Majdan   +3 more
openaire   +2 more sources

Do anti-carbamylated protein antibodies in rheumatoid arthritis reflect local and systemic osteoporosis? A study of osteoprotegrin and receptor activator for nuclear factor kappa B ligand and radiological assessment

Egyptian Rheumatology and Rehabilitation, 2021
Background One of the most important and dangerous complications of rheumatoid arthritis (RA) is bone loss, which manifested by erosions and juxta-articular or systemic bone loss.
Manal Shawky Hussein, Rasha Ahmed Gaber, Hala Mostafa Elsabagh, Elsayed Mohamed Rageh   +3 more
doaj   +1 more source

Anti-carbamylated protein antibody isotype pattern differs between palindromic rheumatism and rheumatoid arthritis

Therapeutic Advances in Musculoskeletal Disease, 2020
Background: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA).
Raul Castellanos-Moreira, Sebastian C. Rodriguez-Garcia, Sonia Cabrera-Villalba, María José Gomara, Georgina Salvador, Virginia Ruiz-Esquide, Julio Ramirez, Jose Inciarte-Mundo, Rosa Morla, Cristina Garcia-Moreno, Andrea Cuervo, Jose A. Gómez-Puerta, Juan D. Cañete, Isabel Haro, Raimon Sanmarti   +14 more
doaj   +1 more source

‘Medusa-head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII [PDF]

, 2015
Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis.
Jarius, Sven, Wildemann, Brigitte
core   +3 more sources

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis. [PDF]

PLoS ONE, 2014
ObjectiveThe immune response to post-translationally modified antigens is a key characteristic of rheumatoid arthritis. Carbamylation is such a posttranslational modification.
Jeroen N Stoop, Bi-Sheng Liu, Jing Shi, Diahann T S L Jansen, Martin Hegen, Tom W J Huizinga, Leendert A Trouw, René E M Toes   +7 more
doaj   +1 more source

The role of Anti-PAD4, Anti-CarP, and Anti-RA33 antibodies combined with RF and ACPA in predicting abatacept response in rheumatoid arthritis. [PDF]

Arthritis Res Ther
To explore the role of newly emerging autoantibodies (AAbs) - peptidyl-arginine deiminase 4 (aPAD4), carbamylated proteins (aCarP), and anti-RA33 (aRA33) - alongside the traditionally assessed rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA), in predicting the response to abatacept (ABT) and its retention rate in rheumatoid ...
Floris A, Angioni MM, Fadda M, Naitza MR, Congia M, Chessa E, Piga M, Cauli A.   +7 more
europepmc   +5 more sources

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis:Results from the Norfolk Arthritis Register [PDF]

, 2015
Objectives: Anticarbamylated protein (anti-CarP) antibodies are a novel family of autoantibodies recently identified in patients with inflammatory arthritis. The aim of this study was to investigate their association with long-term outcomes of disability
Aletaha, Alexander J MacGregor, Anne Barton, Arend, Brink, Burgers, Burska, De, Deborah PM Symmons, Gan, Hecht, Humphreys, Humphreys, Humphreys, Jennifer H Humphreys, Jung, Kosinski, Leendert A Trouw, Marije K Verheul, Mark Lunt, Montes, Nielen, Pope, Quinn, Rene EM Toes, Shi, Shi, Shi, Shidara, Sokolove, Suzanne MM Verstappen, Symmons, van der Helm-van Mil, van der Linden, Wiles, Wolfe, Yee   +36 more
core   +1 more source

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

Arthritis Research & Therapy, 2017
Background Anti-carbamylated protein (anti-CarP) antibodies have recently been reported to occur in around 45% of rheumatoid arthritis (RA) patients and to have prognostic and diagnostic properties.
Myrthe A. M. van Delft, Marije K. Verheul, Leonie E. Burgers, Veerle F. A. M. Derksen, Annette H. M. van der Helm-van Mil, Diane van der Woude, Tom W. J. Huizinga, René E. M. Toes, Leendert A. Trouw   +8 more
doaj   +1 more source

Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies

Frontiers in Immunology, 2021
To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate ...
Pauline Brevet, Pauline Brevet, Claire Lattard, Claire Lattard, Clément Guillou, Pascal Rottenberg, Patrice Fardellone, Xavier Le-Loët, Thierry Lequerré, Thierry Lequerré, Pascal Cosette, Olivier Boyer, Olivier Boyer, Manuel Fréret, Manuel Fréret, Olivier Vittecoq, Olivier Vittecoq   +16 more
doaj   +1 more source