Results 31 to 40 of about 10,780 (181)

Utility of anti-carbamylated protein antibodies in the diagnosis of early rheumatoid arthritis

Indian Journal of Rheumatology, 2019
Background: Anti-carbamylated protein (anti-CarP) antibodies are present in patients with Rheumatoid arthritis (RA) and may present before disease onset.
Ashraf H Mohamed, Asmaa Enein, Noha Abdelsalam, Mona Balata, Sameh Abdellatif, Ehsan Rizk, Ahmed Fathy   +6 more
doaj   +1 more source

Evaluating the Diagnostic Accuracy of Rheumatoid Factor, Anti-citrullinated Protein Antibody and Anti-carbamylated Protein Antibody in Early Detection of Rheumatoid Arthritis: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Rheumatoid Arthritis (RA) is a systemic autoimmune disease that primarily affects synovial joints. Joint infiltration with immune cells is a characteristic feature of RA.
Karthiga Dhakshna Murthi, Anusha Gopinathan, Leela Kakithakara Vajravelu, Thilagam Ramasamy   +3 more
doaj   +1 more source

Anti-carbamylated protein antibodies and skin involvement in patients with systemic sclerosis: An intriguing association.

PLoS ONE, 2018
Carbamylation is a post-translational modification that mostly affects proteins with low turnover, such as dermal proteins. Carbamylated proteins accumulate in skin in an age-dependent manner, contributing to tissue alterations.
Elvira Favoino, Marcella Prete, Serena Vettori, Addolorata Corrado, Francesco Paolo Cantatore, Gabriele Valentini, Federico Perosa   +6 more
doaj   +1 more source

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

Annals of the Rheumatic Diseases, 2013
In juvenile idiopathic arthritis (JIA) patients there is a lack of markers that predict severe disease. Although anticitrullinated protein antibodies (ACPA) have contributed substantially to the understanding of rheumatoid arthritis (RA),1 their detection in JIA has not been equally useful as incidence rates in JIA patients are low2 and merely confined
Muller, P.C.E.H., Anink, J., Shi, J., Levarht, E.W.N., Reinards, T.H.C.M., Otten, M.H., Tol, M.J.D. van, Jol-van der Zijde, C.M., Brinkman, D.M.C., Allaart, C.F., Hoppenreijs, E.P., Koopman-Keemink, Y., Kamphuis, S.S.M., Dolman, K., Berg, J.M. van den, Rossum, M.A.J. van, Suijlekom-Smit, L.W.A. van, Schilham, M.W., Huizinga, T.W.J., Toes, R.E.M., Cate, R. ten, Trouw, L.A.   +21 more
openaire   +4 more sources

Diagnostic Accuracy of IL-17A/IL-17F Gene Polymorphism and Anti-Carbamylated Protein Antibody for Rheumatoid Arthritis: Meta-analysis Study (2014-2020)

SVU - International Journal of Medical Sciences, 2023
Background: The anti-CarP antibody is a novel biomarker that might help in the diagnosis of rheumatoid arthritis. Also, the associations between Interleukin-17A and17F gene polymorphism with inflammatory arthritis were inconsistent among previous studies.
Samar Sayed Ahmed , Mostafa I. El-Amir, Mohamed Ali El-Feky, Eman Ragab Abdelradi   +3 more
doaj   +1 more source

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus

Arthritis Research & Therapy, 2018
Background The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti, Cristiano Alessandri   +11 more
doaj   +1 more source

A5.4 Anti Carbamylated Protein Antibodies (Anti-CarP) Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis [PDF]

Annals of the Rheumatic Diseases, 2013
Background/Objective Recently, we discovered a new auto- antibody system in rheumatoid arthritis (RA): anti carbamylated protein antibodies (anti-CarP). These antibodies have additional prognostic value in predicting joint destruction when compared to anti-citrullinated protein antibodies (ACPA).
Jing Shi, Lotte A van de Stadt, EW Nivine Levarht, Tom WJ Huizinga, René EM Toes, Leendert A Trouw, Dirkjan van Schaardenburg   +6 more
openaire   +1 more source

Erratum to: Anti-CarP antibodies as promising marker to measure joint damage and disease activity in patients with rheumatoid arthritis [PDF]

Immunologic Research, 2015
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Yee, Alvin, Webb, Tyler, Seaman, Andrea, Infantino, Maria, Meacci, Francesca, Manfredi, Mariangela, Benucci, Maurizio, Lakos, Gabriella, Favalli, Ennio, Schioppo, Tommaso, Meroni, Pier-Luigi, Mahler, Michael   +11 more
openaire   +2 more sources

OP0178 Antibodies against Carbamylated Proteins (ANTI-CARP), A New Type of Autoantibody, in Spanish Patients with Rheumatoid Arthritis [PDF]

Annals of the Rheumatic Diseases, 2014
Background Antibodies against carbamylated proteins (anti-CarP) are a new type of autoantibodies present in sera of patients with rheumatoid arthritis (RA). These antibodies, measured as the reactivity against carmabylated proteins from Fetal Calf Serum (FCS), do not show cross-reactivity with anti-CCP antibodies, and are associated with radiologic ...
A. Montes, E. Perez-Pampín, M.D. Bόveda, J.J. Gόmez-Reino, A. González   +4 more
openaire   +6 more sources

Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy

BMC Musculoskeletal Disorders, 2021
Background Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50–60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients for anti-TNF therapy.
Antonio Julià, María López-Lasanta, Francisco Blanco, Antonio Gómez, Isabel Haro, Antonio Juan Mas, Alba Erra, Ma Luz García Vivar, Jordi Monfort, Simón Sánchez-Fernández, Isidoro González, Mercedes Alperi, Raúl Castellanos-Moreira, Antonio Fernández-Nebro, César Díaz-Torné, Núria Palau, Raquel Lastra, Jordi Lladós, Raimon Sanmartí, Sara Marsal   +19 more
doaj   +1 more source