Effect of Etanercept on anti-carbamylated protein antibodies in patients with rheumatoid arthritis [PDF]
, 2015 Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e.
Alessandri, Cristiano +4 more
core +1 more source
Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]
, 2016 Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano +16 more
core +1 more source
FRI0040 Characterization of anti-carbamylated synovial protein antibodies (ANTI-CARPS) in rheumatoid arthritis patients [PDF]
Annals of the Rheumatic Diseases, 2017 Background Anti-carbamylated protein antibodies (anti-CarP) are a new type of autoantibodies specific of patients with RA. Reactivity has generally been tested with in vitro carbamylated proteins from fetal calf serum (FCS) as anti-CarPF. It is likely that other sources of antigens could be more suitable than FCS unless the reactivity of the ...
C Regueiro +6 more
openaire +1 more source
MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF [PDF]
, 2016 BACKGROUND: In rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-citrullinated protein antibodies (ACPA) are associated with radiographic progression.
Annette H. M. van der Helm-van Mil +7 more
core +3 more sources
Anais da Academia Brasileira de Ciências, 2021 Until now, custom-made or commercial polyclonal antibody against only one kind of fish IgM limited application of the antibody. During our research on development of vaccine against infection of Clonorchis sinensis (C. sinensis) in several kinds of fish,
XINYI ZHOU +11 more
doaj +1 more source
Arthritis Research & Therapy, 2017 Background Rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) and anti-carbamylated protein (anti-CarP) antibodies are rheumatoid arthritis (RA)-associated autoantibodies. Besides their presence in human serum, anti-CarP antibodies have
Marije K. Verheul +4 more
doaj +1 more source
RMD Open, 2022 Background Predicting progression to clinical arthritis in individuals at-risk of developing rheumatoid arthritis is a prerequisite to developing stratification groups for prevention strategies. Selecting accurate predictive criteria is the critical step
Paul Emery +7 more
doaj +1 more source
Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se:a multicenter cohort study [PDF]
, 2016 BACKGROUND: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA).
Ajeganova, Sofia +24 more
core +1 more source
Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production [PDF]
, 2017 BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual’s life.
Ana L. Alemán-Navarro +12 more
core +1 more source
Meta-Analysis: Diagnostic Accuracy of Anti-Carbamylated Protein Antibody for Rheumatoid Arthritis. [PDF]
PLoS ONE, 2016 The anti-carbamylated protein (CarP) antibody is a novel biomarker that might help in the diagnosis of rheumatoid arthritis (RA). We aim to assess the diagnostic value of anti-CarP antibody for RA.We systematically searched PubMed, Embase, the Cochrane ...
Liubing Li +7 more
doaj +1 more source