Results 101 to 110 of about 24,348 (233)

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo   +8 more
wiley   +1 more source

an interim analysis from the observational, prospective ACTION study [PDF]

open access: yes, 2015
Background The emergence of new therapies for the treatment of rheumatoid arthritis (RA), the paucity of head-to-head studies, and the heterogeneous nature of responses to current biologics highlight the need for the identification of prognostic factors ...
Alten, Rieke   +12 more
core   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

Rheumatoid arthritis, item response theory, Blom transformation, and mixed models [PDF]

open access: yes, 2007
We studied rheumatoid arthritis (RA) in the North American Rheumatoid Arthritis Consortium (NARAC) data (1499 subjects; 757 families). Identical methods were applied for studying RA in the Genetic Analysis Workshop 15 (GAW15) simulated data (with a prior
Borecki, Ingrid B   +7 more
core   +2 more sources

Association of cardiovascular risk factors with carotid intima media thickness in patients with rheumatoid arthritis with low disease activity compared to controls: A cross-sectional study [PDF]

open access: yes, 2015
Objectives Rheumatoid arthritis (RA) has been identified as an independent cardiovascular risk factor. The importance of risk factors such as hypertension and hyperlipidemia in the generation of atherosclerosis in RA patients is unclear.
Birnie, E. (Erwin)   +9 more
core   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

open access: yesRheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen   +6 more
wiley   +1 more source

Is anti-cyclic citrullinated peptide antibody a good value biomarker for alzheimer disease?

open access: yesInternational Journal of Preventive Medicine, 2013
Background: Alzheimer′s disease (AD) is one of the most important neurodegenerative disorder. Anti-cyclic citrullinated peptide (anti-CCP) may all be involved in the development of vascular disease such as AD.
Rokhsareh Meamar   +6 more
doaj  

Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case-control study [PDF]

open access: yes, 2018
Introduction: Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA heritability.
Balsa, Alejandro   +17 more
core   +1 more source

Entwined Liberations: North Korean Democratic Women's Union and Third World Internationalism, 1945–1949

open access: yesGender &History, EarlyView.
ABSTRACT This research focuses on how the North Korean Democratic Women's Union (NKDWU), the umbrella women's organisation in North Korea formed soon after Korea's liberation from Japanese colonial rule in 1945, forged international leftist women's solidarity during the North Korean state's liminal, revolutionary period (1945–1949).
Taejin Hwang
wiley   +1 more source

Association of CD247 polymorphisms with rheumatoid arthritis: a replication study and a meta-analysis [PDF]

open access: yes, 2016
Given the role of CD247 in the response of the T cells, its entailment in autoimmune diseases and in order to better clarify the role of this gene in RA susceptibility, we aimed to analyze CD247 gene variants previously associated with other autoimmune ...
Balsa, Alejandro   +12 more
core   +1 more source

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