Results 111 to 120 of about 24,348 (233)

A Population‐Based Matched Cohort Study of Extra‐Digestive Cancer Incidence and Mortality in Individuals With and Without Inflammatory Bowel Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
This illustration summarises our primary findings highlighting the rising incidence of certain extra‐digestive cancers among persons with IBD over the 25‐year study duration (left), and the relative rates of extra‐digestive cancer incidence and mortality among persons with IBD in recent years (2010–2019) compared to their age‐ and sex‐matched controls (
Sanjay K. Murthy, Faria Ahmed, Michael Pugliese, Monica Taljaard, Parul Tandon, Priscilla Matthews, Gilaad G. Kaplan, Stephanie Coward, Charles N. Bernstein, Eric I. Benchimol, M. Ellen Kuenzig, Laura E. Targownik, Harminder Singh, on behalf of the Canadian Gastro‐Intestinal Epidemiology Consortium (CanGIEC)   +13 more
wiley   +1 more source

Tsitrullineeritud peptiidi vastased antikehad reumatoidartriidi diagnostikas [PDF]

, 2004
Reumatoidartriit on krooniline süsteemne põletikuline haigus, mis haarab peamiselt liigeseid ja võib viia nende destruktsioonini. Haiguse seroloogiline diagnostika on siiani olnud piiratud ja mittespetsiifiline. Kuna nüüdisaegse reumatoidartriidi ravi
Suigom , Mare
core   +2 more sources

Valor diagnóstico do anticorpo antipeptídeo citrulinado cíclico na artrite reumatóide Diagnostic value of anti-cyclic citrullinated peptide antibody in rheumatoid arthritis

Revista Brasileira de Reumatologia, 2006
INTRODUÇÃO: a artrite reumatóide (AR) é considerada uma das doenças auto-imunes mais freqüentes, mas um teste viável e específico para seu diagnóstico não está disponível.
Aldifran Ferreira da Silva, Afonso Napoleão Matos, Áurea Maria Santana Lima, Elízia Fernandes Lima, Antônio Pinheiro Gaspar, José Antônio Fortes Braga, Edgar M. Carvalho   +6 more
doaj   +1 more source

Autoantibodies in inflammatory arthritis [PDF]

, 2016
Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease characterized by extensive synovitis resulting in erosions of articular cartilage and marginal bone with joint destruction.
Chimenti, Ms, Conigliaro, P, Novelli, L, Perricone, C, Perricone, R, Sunzini, F, Triggianese, P   +6 more
core   +1 more source

Long‐term remission of type B insulin resistance syndrome with immunotherapy: A case report

Journal of Diabetes Investigation, EarlyView.
ABSTRACT We report long‐term remission in a patient with type B insulin resistance achieved with a combination of immunotherapies. A 55‐year‐old Japanese man presented with nocturnal hypoglycemia and cytopenia. He also had postprandial hyperglycemia due to severe insulin resistance, which was difficult to manage using high‐dose insulin and recombinant ...
Erika Egawa, Rei Karasawa, Yuka Kageyama, Kazuhiko Takaya   +3 more
wiley   +1 more source

Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthritis

International Journal of Medical Sciences, 2011
Objective/Aim: A new group of autoantibodies in Rheumatoid Arthritis (RA), the anti-cyclic citrullinated peptide (anti-CCP) antibodies directed to citrulline-containing proteins, which are of value for the severity of RA.
Levent Ediz, Ozcan Hiz, Halil Ozkol, Elif Gulcu, Murat Toprak, Mehmet Fethi Ceylan
doaj  

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile [PDF]

, 2012
OBJECTIVES: To increase understanding of the aetiology and pathogenesis of rheumatoid arthritis (RA), genetic and environmental risk factors for RA subsets, defined by the presence or absence of different anticitrullinated protein/peptide antibodies ...
Alfredsson, Lars, Bengtsson, Camilla, Holmdahl, Rikard, Israelsson, Lena, Jiang, Xia, Kessel, Christoph, Kharlamova, Nastya, Klareskog, Lars, Källberg, Henrik, Lundberg, Karin, Padyukov, Leonid, Pollak-Dorocic, Iskra, Reed, Evan   +12 more
core   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Anti-Cyclic Citrullinated Peptide (Anti-CCP) and Anti-Mutated Citrullinated Vimentin (Anti-MCV) Relation with Extra-Articular Manifestations in Rheumatoid Arthritis

Journal of Immunology Research, 2014
We evaluated the association between anti-cyclic citrullinated peptide antibodies (anti-CCP) and anti-mutated citrullinated vimentin antibodies (anti-MCV) with the presence of extra-articular (ExRA) manifestations in 225 patients with rheumatoid ...
Laura Gonzalez-Lopez, Alberto Daniel Rocha-Muñoz, Manuel Ponce-Guarneros, Alejandra Flores-Chavez, Mario Salazar-Paramo, Arnulfo Nava, Ernesto German Cardona-Muñoz, Nicte Selene Fajardo-Robledo, Soraya Amali Zavaleta-Muñiz, Teresa Garcia-Cobian, Jorge Ivan Gamez-Nava   +10 more
doaj   +1 more source

Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis

RMD Open, 2019
Objective Antibodies to citrullinated peptides (anti-CCP) develop in individuals predisposed to rheumatoid arthritis (RA). Neutrophil extracellular traps are a major source of citrullinated antigens and the immunomodulatory host defence peptide LL-37 ...
Carol A Hitchon, Xiaobo Meng, Hani S El Gabalawy, Linda Larcombe   +3 more
doaj   +1 more source