Ultrasound subclinical synovitis in anti-CCP-positive at-risk individuals with musculoskeletal symptoms: an important and predictable stage in the rheumatoid arthritis continuum. [PDF]
Di Matteo A +8 more
europepmc +1 more source
Meningococcal Serogroup Y Meningitis Reveals Inborn Factor B Deficiency
We report a novel case of complete complement Factor B deficiency revealed by invasive meningococcal disease. Using combined functional and genetic analyses, we demonstrate that loss of Factor B abolishes alternative pathway activity despite detectable protein levels. These findings provide a mechanistic framework relevant to complement diagnostics and
Camille Bougeard +9 more
wiley +1 more source
The influence of the -94 Ins/Del ATTG polymorphism of NFkB on the anti-CCP antibody levels in patients with rheumatoid arthritis. [PDF]
Ayón-Pérez MF +8 more
europepmc +1 more source
Longan flower water extract promotes sleep in mice via the serotonin–melatonin axis
Abstract BACKGROUND Longan (Dimocarpus longan) flower is an underutilized botanical byproduct rich in polyphenols with reported neuroprotective actions, yet its role in sleep regulation remains unclear. This study aimed to evaluate the sleep‐promoting effects of longan flower water extract (LFWE) and its underlying neurochemical mechanisms in vivo ...
Tzu‐Huan Hung +9 more
wiley +1 more source
Increased CRP, anti-CCP antibody, IL-2R, COMP levels in prognosis of post-chikungunya chronic arthritis and protective role of their specific genotypes against arthritic manifestation. [PDF]
Sengupta S, Bhattacharya N, Tripathi A.
europepmc +1 more source
Precision medicine in orthopaedics: A review of current technologies and future directions
Abstract Purpose To synthesise the paradigm shift towards precision medicine in orthopaedics, where individual anatomical, biomechanical, molecular and kinematic characteristics are integrated into clinical decision‐making. Unlike traditional approaches applying uniform protocols, this review outlines how precision orthopaedics aims to tailor surgical ...
Patrick Sadoghi +5 more
wiley +1 more source
PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking. [PDF]
Massarenti L +8 more
europepmc +1 more source
One year in review: ultrasound in arthritis [PDF]
Musculoskeletal ultrasound (MSUS) has become a relevant part of rheumatology practice and research because it substantially allows us to optimize management of rheumatic and musculoskeletal diseases. This non-invasive imaging modality is a valuable point-
IAGNOCCO, Annamaria, Naredo, Esperanza
core
We present a case of ILD preceding RA onset. The disease activity of arthritis and ILD was controlled, and ILD was stabilised for 4 years with the JAK1 selective inhibitor, filgotinib. ABSTRACT We present a case of active interstitial lung disease (ILD) preceding the onset of rheumatoid arthritis (RA).
Takeo Sato +4 more
wiley +1 more source
Correction to: A Closer Look at the Role of Anti-CCP Antibodies in the Pathogenesis of Rheumatoid Arthritis Associated Interstitial Lung Disease and Bronchiectasis. [PDF]
Khan T, José RJ, Renzoni EA, Mouyis M.
europepmc +1 more source

