Results 71 to 80 of about 24,348 (233)

Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience

Viruses, 2021
Background: COVID-19 convalescent plasma (CCP) has been considered internationally as a treatment option for COVID-19. CCP refers to plasma collected from donors who have recovered from and made antibodies to SARS-CoV-2.
Tanya Nadia Glatt, Caroline Hilton, Cynthia Nyoni, Avril Swarts, Ronel Swanevelder, James Cowley, Cordelia Mmenu, Thandeka Moyo-Gwete, Penny L. Moore, Munzhedzi Kutama, Jabulisile Jaza, Itumeleng Phayane, Tinus Brits, Johan Koekemoer, Ute Jentsch, Derrick Nelson, Karin van den Berg, Marion Vermeulen   +17 more
doaj   +1 more source

Correlation of Autoantibodies with the Disease Activity Score 28 and Radiographic Hand Joint Damage in Rheumatoid Arthritis Patients [PDF]

, 2010
Background: Rheumatoid arthritis (RA) is a systemic chronic infl ammatory disease of the joint that causes deformity or disability leading to a decreased function in RA patients.
Isbagio, H. (Harry), Manuaba, I. A. (Ida), Sumariyono, S. (Sumariyono)   +2 more
core  

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]

, 2005
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
A Bucht, AN Akbar, AN Akbar, Arne N Akbar, B Relic, BP Leung, C Jakubzick, Caroline Gordon, CD Buckley, CD Buckley, Chi-Yeung Lee, Christopher D Buckley, CM Weyand, D Pilling, DV Jovanovic, E Berglin, Emma J Ross, F Fossiez, F Santiago-Schwarz, FC Arnett, FM Brennan, FP Heinzel, Francesco Falciani, G Husby, G Parsonage, GS Firestein, GS Firestein, GS Firestein, H Visser, HR Schumacher, IB McInnes, J Kaufman, Janet M Lord, JM Bathon, K Raza, Karim Raza, L Breiman, LA Joosten, LJ Zhou, M Boers, M Salmon, M Salmon, M Sebbag, MC Blades, MG Chiaramonte, Mike Salmon, MJ Jacobs, MM Nielen, N Matthews, NJ Zvaifler, P Kurki, P Miossec, PG Conaghan, PK Gregersen, PP Tak, R Bucala, R Gerli, RL Modlin, S John Curnow, SJ Curnow, SK Seo, T Mottonen, T Pap, TF Cox, Y Benjamini, Y Morita   +65 more
core   +2 more sources

Anti-CCP antibodies: the past, the present and the future

Nature Reviews Rheumatology, 2011
Rheumatoid arthritis (RA) is an autoimmune disease characterized by autoantibodies against citrullinated antigens. The importance of citrulline for the epitopes bound by these autoantibodies, referred to as ACPA (anti-citrullinated peptide/protein antibodies), was first described in 1998.
van Venrooij, W.J.W., van Beers, J.J.B.C., Pruijn, G.J.M., Pruijn, G.J.M.   +3 more
openaire   +3 more sources

Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive.
Viola Pitkänen, Terhi Remes‐Pakarinen, Paula Vähäsalo, Milja Möttönen, Minna‐Maija Grönlund, Miika Arvonen, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Johanna Lempainen, Anna‐Mari Schroderus, Liisa Kröger, Tuure Kinnunen   +13 more
wiley   +1 more source

Correlation between Anti-CCP Titer and Body Mass Index Score in Rheumatoid Arthritis Patients in Cipto Mangunkusumo Hospital

Indonesian Journal of Rheumatology, 2018
Background: Rheumatoid Arthritis (RA) is a chronic systemic inflammation that attacks and damages joints of upper and lower extremities. RA causes morbidity and disability, hence, affects the quality of life.
Harry Isbagio, Khadijah Fitriah
doaj   +1 more source

A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibodies – a role in rheumatoid arthritis and the possibility of seroconversion: A focus on abatacept

Современная ревматология, 2017
The detection of anti-cyclic citrullinated peptide (anti-CCP) antibodies plays a diagnostic and statistical predictive role in rheumatoid arthritis (RA).
N. V. Chichasova
doaj   +1 more source

Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis [PDF]

, 2009
Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been ...
Arnold, Sybille, Baerwald, Christoph, Burkhardt, Harald, Keyßer, Gernot, Pierer, Matthias, Rossol, Manuela, Wagner, Ulf   +6 more
core   +2 more sources

Performance of an Idiopathic Pulmonary Fibrosis–Derived Multibiomarker Panel for Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective To assess whether a panel of peripheral blood biomarkers associated with idiopathic pulmonary fibrosis (IPF) is also associated with interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) using three independent cohorts. Methods We first assessed the association of a panel of IPF‐associated biomarkers with prevalent ILD ...
Brent A. Luedders, Daniel Kass, Joshua F. Baker, Michael J. Duryee, Yangyuna Yang, Punyasha Roul, Halie Frideres, Katherine D. Wysham, Paul A. Monach, Andreas Reimold, Gail S. Kerr, Gary Kunkel, Grant W. Cannon, Scott M. Matson, Jill A. Poole, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England, Dana P. Ascherman   +18 more
wiley   +1 more source