Results 131 to 140 of about 69,669 (257)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

open access: yesExploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang   +8 more
wiley   +1 more source

Effect of Microchannel Geometry on Nanoparticle Deposition in Nanofluid Flow

open access: yesInternational Journal for Numerical Methods in Fluids, EarlyView.
This study numerically analyzed nanoparticle deposition in microchannels with varying geometries. Deposition per unit area decreases significantly with increasing bend angle (28.612 to 8.941 between 30° and 120°) and bend radius (11.922 to 4.769 between 0.2 and 0.4 mm). Acute bends and small radii enhance centrifugal forces and flow separation, leading
Meng Wang   +3 more
wiley   +1 more source

On the Variability of Results for Cylinder Flow: A Systematic Analysis of Parameter Sensitivity Within the Lattice Boltzmann Method

open access: yesInternational Journal for Numerical Methods in Fluids, EarlyView.
This study systematically investigates the variability of cylinder flow results. We provide a comprehensive overview of literature values and, using the lattice Boltzmann method (LBM), show that insufficient convergence studies and variations in simulation parameters are a plausible cause for the significant spread in data.
Maximilian Bille   +4 more
wiley   +1 more source

Recent advances in multifunctional soft robots: A materials–structures–systems co‐design perspective for synergistic integration

open access: yesFlexMat, EarlyView.
Abstract Soft robots, engineered from highly compliant materials, offer superior adaptability and safety in unstructured environments compared to their rigid counterparts. Recent advancements, fueled by bio‐inspiration and material programmability, have led to the rapid co‐evolution of their core modules: actuation, sensing, protection, energy, and ...
Qiulei Liu   +3 more
wiley   +1 more source

Triboelectric nanogenerators for vehicle intelligent cockpits

open access: yesFlexMat, EarlyView.
Converting mechanical stimuli from drivers and vehicle motion into electrical signals, triboelectric nanogenerators provide promising interfaces toward passive, flexible, distributed and intelligent sensing for next‐generation automotive cockpits to support three core functional dimensions: driver state monitoring, vehicle state monitoring, and human ...
Haiqiu Tan   +9 more
wiley   +1 more source

New Thermal Lattice Boltzmann Method for Modeling Heat Transfer Problems Considering Temperature‐Dependent Properties

open access: yesHeat Transfer, EarlyView.
ABSTRACT Several engineering problems involve the need to model conjugate heat transfer processes considering the temperature‐dependence of the material properties. Consequently, a simulation tool capable of modeling this process is of great interest. In this context, the present work proposes a thermal lattice Boltzmann method (TLBM) for modeling the ...
Julia Akiko Sassa   +2 more
wiley   +1 more source

Recent Advances in Luminescent Hydrogen‐Bonded Organic Frameworks (HOFs): Linker Design, Phosphorescence, and Smart Responsiveness

open access: yesInformation &Functional Materials, EarlyView.
Luminescent Hydrogen‐bonded organic frameworks (HOFs) provide an innovative platform for sensing and optoelectronic applications. This review outlines design principles, recent advances in synthesis and optical tuning, diverse sensing applications, and discusses current challenges and future directions for HOFs.
Heng Wu   +4 more
wiley   +1 more source

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