Results 171 to 180 of about 197,173 (246)

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar   +10 more
wiley   +1 more source

Hierarchical Disruption of the Tryptophan–Melatonin Axis Contributes to Glioma Progression Through AKT/ERK/STAT3 Signalling

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Melatonin signalling, mediated by membrane receptors and tightly regulated biosynthetic enzymes, is a key component of circadian and neuroendocrine control in the brain. However, whether the tryptophan–melatonin axis remains hierarchically intact during glioma progression and how its disruption affects downstream signalling remain unclear.
Bo Tan   +11 more
wiley   +1 more source

Overexpression of key complement regulators in glioblastoma. [PDF]

open access: yesPLoS One
Blomberg L   +4 more
europepmc   +1 more source

METTL3/YTHDF1‐Driven SURF6 Promotes Prostate Cancer Stemness via CDK4

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Prostate cancer (PCa) remains a major health challenge globally, necessitating the identification of novel therapeutic targets to improve patient outcomes. This study investigates the role of the SURF6 gene in PCa, focusing on its expression patterns, molecular mechanisms, and biological behaviours in vitro and in vivo.
Yue Cheng   +3 more
wiley   +1 more source

Intersecting Autoimmunities: ANCA and Anti-GBM Overlap in a Patient With Sjögren's Disease. [PDF]

open access: yesCase Rep Nephrol
Estacio M   +3 more
europepmc   +1 more source

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