Results 171 to 180 of about 197,173 (246)
Targeting regulatory T cells in glioblastoma: from mechanistic insights to novel immunotherapeutic strategies. [PDF]
Li J, Liu Y, Peng P, Hu J.
europepmc +1 more source
Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
wiley +1 more source
tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar +10 more
wiley +1 more source
Antiglomerular Basement Membrane (Anti-GBM) Glomerulonephritis in the Context of Genitourinary Tuberculosis: A Case Report. [PDF]
Tan SM +4 more
europepmc +1 more source
ABSTRACT Melatonin signalling, mediated by membrane receptors and tightly regulated biosynthetic enzymes, is a key component of circadian and neuroendocrine control in the brain. However, whether the tryptophan–melatonin axis remains hierarchically intact during glioma progression and how its disruption affects downstream signalling remain unclear.
Bo Tan +11 more
wiley +1 more source
Overexpression of key complement regulators in glioblastoma. [PDF]
Blomberg L +4 more
europepmc +1 more source
METTL3/YTHDF1‐Driven SURF6 Promotes Prostate Cancer Stemness via CDK4
ABSTRACT Prostate cancer (PCa) remains a major health challenge globally, necessitating the identification of novel therapeutic targets to improve patient outcomes. This study investigates the role of the SURF6 gene in PCa, focusing on its expression patterns, molecular mechanisms, and biological behaviours in vitro and in vivo.
Yue Cheng +3 more
wiley +1 more source
Intersecting Autoimmunities: ANCA and Anti-GBM Overlap in a Patient With Sjögren's Disease. [PDF]
Estacio M +3 more
europepmc +1 more source
Kidney. Rapid progressive nephritis and ANCA - the anti-GBM antibody.
openaire +2 more sources

