Results 231 to 240 of about 197,173 (246)

Glomerular Basement Membrane and Anti-GBM Antibody Disease

Nephron, 2008
The GBM is an important structure for the development of immunologic renal disease. It may serve as the primary antigen or as the site of deposition of immune complexes. The GBM is recognized as the major protein filtration barrier of the glomerulus.
openaire   +2 more sources

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease

Nephrology Dialysis Transplantation, 2009
Background. Although the clinical importance of demonstrating the presence of anti-glomerular basement membrane (anti-GBM) antibodies is well established, less is known concerning the clinical utility of measuring the levels of autoantibodies.
Rui Yang, Thomas Hellmark, Zhao Cui
exaly   +2 more sources

Anti-GBM antibody-induced proteinuria in isolated perfused rat kidney

American Journal of Physiology-Renal Physiology, 1985
The effect of anti-GBM antibody on protein excretion was studied in isolated rat kidneys perfused with 20 mg of sheep anti-rat GBM (experimental) or nonantibody sheep IgG (control). Six control kidneys excreted 176 +/- 31 micrograms/min of BSA initially, rising to 296 +/- 111 micrograms/min at 2 h.
W G, Couser, C, Darby, D J, Salant, S, Adler, M M, Stilmant, L M, Lowenstein   +5 more
openaire   +2 more sources

Diabetic nephropathy with interstitial nephritis presenting with a false-positive anti-GBM antibody

Clinical Nephrology, 2002
A 56-year-old male with DM and HTN presented with flank pain and nausea. Review of systems was negative, physical examination was notable for mild hypovolemia and laboratory revealed BUN 51 mg/dl, creatinine (Cr) 5.1 mg/dl (baseline 1.5), Westergren ESR 122 mm/h, fractional excretion of sodium 0.2% and UA positive for blood and protein.
A J, DeAangelo, K J, Lancaster-Weiss, S, Eliason, D, Troyer, W G, Wortham   +4 more
openaire   +2 more sources

Anti-GBM antibody in a patient with diabetic nephropathy; all that glitters is not gold

Journal of Nephrology
We present the case of a 58-year-old male diabetic patient admitted to our department for a slight decrease in kidney function, with nephrotic range proteinuria, hematuria (16,000/ml) and positive anti-glomerular basement membrane antibodies. Kidney biopsy revealed diabetic nephropathy with no evidence of crescent formation or linear immunoglobulin ...
Pedram Ahmadpoor, Florian Garo, Laure Patrier, Moise Michel, Olivier Moranne   +4 more
openaire   +2 more sources

ANCA-associated vasculitis, anti-GBM positive vasculitis, and double positive patients (ANCA and anti-GBM antibodies) with renal progress and survival

Clinical Nephrology
Double antibody-positive patients (DPP) have vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCA) and anti-glomerular basement membrane (GBM) disease. This is a rare and under-described condition. The present study aimed to compare renal function and characteristics between DPP and patients with ANCA-associated vasculitis (AAV) and ...
Musa Ilker, Durak, Beyza, Algul Durak, Naim, Ata, Mahir, Ülgü, Şuayip, Birinci, Sinem, Can   +5 more
openaire   +2 more sources

Antibodies: Still Important in Anti-GBM Disease

Nephron Clinical Practice, 2004
openaire   +2 more sources

99 Histological and Clinical Anti-GBM Disease With MPO-ANCA but Without Circulating Anti-GBM Antibodies

American Journal of Kidney Diseases, 2023
openaire   +1 more source

Epitope mapping of anti-glomerular basement membrane (GBM) antibodies with synthetic peptides

Clinical and Experimental Immunology, 2003
Thomas Hellmark, Jorgen Wieslander
exaly  

Routinely used immunoassays do not detect circulating anti‐GBM antibodies against native NC1 hexamer and EA epitope of the α3 chain of type IV collagen

European Journal of Immunology, 2018
Giovanna Clavarino, Thomas Hellmark, Marie-Agnes Dragon-Durey   +2 more
exaly