Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report [PDF]
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +4 more sources
Anti-GBM Disease in Pregnancy [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2015 Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease.
Mohammed Muqeet Adnan MD +5 more
doaj +3 more sources
Veno-venous extracorporeal membrane oxygenation (VV-ECMO) for life-threatening isolated pulmonary anti-GBM disease [PDF]
Respiratory Medicine Case Reports, 2022 Anti-glomerular basement membrane disease (anti-GBM disease) associated with renal and lung lesions has a poor prognosis. Diffuse alveolar hemorrhage (DAH) is a complication that worsens anti-GBM disease prognosis.
Shogo Goda +2 more
doaj +2 more sources
Relationship Between Serum Complement C3 Levels and Outcomes Among Patients With Anti-GBM Disease [PDF]
Frontiers in Immunology, 2022 BackgroundIgG and complement 3 (C3) are generally found to be deposited along the glomerular basement membrane (GBM) in human anti-GBM disease. The pathogenic role of complement activation in kidney damage of anti-GBM disease has been explored in recent ...
Mengyue Zhu +6 more
doaj +2 more sources
A case of aggressive atypical anti-GBM disease complicated by CMV pneumonitis [PDF]
BMC Nephrology, 2019 Background Anti-glomerular basement membrane (anti-GBM) disease is characterized by circulating IgG glomerular basement membrane antibodies and is clinically expressed as a rapidly progressive crescentic glomerulonephritis (GN), with 30–60% of patients ...
Barbora Sporinova +6 more
doaj +2 more sources
Peroxidasin-a Novel Autoantigen in Anti-GBM Disease? [PDF]
J Am Soc Nephrol, 2018 Basement membranes are highly specialized extracellular matrices, the evolution of which coincided with the emergence of multicellularity in animals. They associate with all epithelial and endothelial surfaces in the body, and they are essential for tissue morphogenesis both through provision ...
McAdoo SP, Pusey CD.
europepmc +5 more sources
Clinical features and prognosis of patients with anti-GBM disease combined with mesangial IgA deposition [PDF]
Frontiers in ImmunologyIntroductionAnti-GBM diseases with IgA deposition in the mesangial region are rarely described.The factors influencing renal prognosis in patients with anti-GBM disease combined with mesangial IgA deposition are unknown.MethodsWe searched the ...
Wei Ning +11 more
doaj +2 more sources
Recurrent anti-GBM disease with pulmonary artery aneurysms. [PDF]
JRSM Open, 2016 We present the first known case of pulmonary artery aneurysms as a feature of Recurrent Anti-Glomerular Basement Membrane disease.
Dixon J, Wilkinson H, Iqbal K, Quan V.
europepmc +4 more sources
Plasmapheresis, immunosuppressive therapy and anti-GBM disease prognosis: a cohort study of 107 patients [PDF]
Renal FailureBackground Anti-glomerular basement membrane (anti-GBM) disease presents with rapidly progressive glomerulonephritis and alveolar hemorrhage, requiring urgent management.
Ying Liu +11 more
doaj +2 more sources
Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review [PDF]
Frontiers in ImmunologyBackgroundLong-standing rheumatoid arthritis (RA) complicated by anti–glomerular basement membrane (anti-GBM) disease is exceptionally rare.CaseA 71-year-old man with long-standing seropositive RA developed a rapidly progressive glomerulonephritis due to
Ji Li +11 more
doaj +2 more sources