Results 101 to 110 of about 71,827 (185)

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

Serum matrix metalloproteinase-9 levels and enzymatic activity in patients with anti-glomerular basement membrane disease

Frontiers in Medicine
BackgroundAnti-glomerular basement membrane (anti-GBM) disease is an autoimmune disorder with autoantibodies against GBM component, non-collagenous domain of the α3 chain of type IV collagen, α3(IV)NC1. Matrix metalloproteinase-9 (MMP-9) is an endogenous
Huang Kuang, Huang Kuang, Huang Kuang, Huang Kuang, Hong-shan Wan, Hong-shan Wan, Hong-shan Wan, Hong-shan Wan, Qiu-hua Gu, Qiu-hua Gu, Xiao-yu Jia, Xiao-yu Jia, Xiao-yu Jia, Xiao-yu Jia, Zhao Cui, Zhao Cui, Zhao Cui, Zhao Cui, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao   +21 more
doaj   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Anti-GBM Disease after Oxford-AstraZeneca ChAdOx1 nCoV-19 Vaccination: A Report of Two Cases. [PDF]

Case Rep Nephrol Dial, 2022
Coorey CP, Phua E, Chou A, Shen Y, Mather A.   +4 more
europepmc   +1 more source

Predicting Pressure Injury Prevention Education by Acute Care Nurses Within 24 h of Hospital Admission: A Cross‐Sectional Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Predicting medical/surgical nurses' delivery of patient pressure injury prevention education within 24 h of hospitalisation. Design A cross‐sectional sub‐study drawn from a larger multisite randomised controlled trial. Methods A consecutive sub‐sample of 300 randomly assigned control group participants was recruited from 20 medical and ...
Jodie Lee Deakin, Sharon Leanne Latimer, Rachel M. Walker, Brett Dyer, Brigid Mary Gillespie   +4 more
wiley   +1 more source

ANCA-Associated Vasculitis With Anti-GBM Disease and Two Types of Tumors: A Case Report. [PDF]

Front Med (Lausanne), 2021
Li X, Huang M, Liu J.
europepmc   +1 more source

Clinical significance of renal histological diagnosis in patients with type 2 diabetes and proteinuria atypical for diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background/Aim Most patients with proteinuria are considered to have typical diabetic nephropathy (DN). However, when proteinuria occurs without diabetic retinopathy, with hematuria, or persists despite strict glycemic and blood pressure control, it is considered atypical for DN and warrants further evaluation for non‐DN via kidney biopsy ...
Shogo Kuwagata, Masami Chin‐Kanasaki, Aki Yamada, Tomonori Sakae, Nahomi Ishimoto, Yoshimi Imamura‐Uehara, Kosuke Yamahara, Mako Yasuda‐Yamahara, Sho Sugahara, Yuki Tanaka‐Sasaki, Natsumi Kuwata, Kimihiro Nishimura, Koichiro Murata, Itsuko Miyazawa, Shogo Ida, Natsuko Ohashi, Shinji Kume   +16 more
wiley   +1 more source

Sequential development of ANCA-associated vasculitis and anti-GBM disease: A report of two cases. [PDF]

Clin Case Rep, 2021
Le Moine C, Jourde-Chiche N, Kemlin D, Terrier B, Vandergheynst F.   +4 more
europepmc   +1 more source

Cancer‐associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi‐omics and machine learning analysis

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Fibroblastic proliferation in various tumor microenvironments influences cancer survival through complex interactions with diverse immune responses. This study investigated the impact of histologically unique activated cancer‐associated fibroblasts (aCAFs) on survival outcomes and immune responses and examined their association with various ...
Myungsun Shim, One‐Zoong Kim, Byoung Kwan Son, Jung Ki Jo, Seung Wook Lee, Hong Sang Moon, Hyung Suk Kim, Mi Jung Kwon, Sung Hak Lee, Yung‐Kyun Noh, Kyueng‐Whan Min   +10 more
wiley   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source