Results 21 to 30 of about 22,460 (165)

Anti-glomerular basement membrane disease [PDF]

Kidney International, 2003
Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD, Harrington, JT, Dasgupta, I, Feehally, J, Rees, A, Hughes, J, Singh, A, Savage, C, Salama, A, Winearls, C, Tomson, C, Mathieson, P, Oliveira, D, Nelson, W   +13 more
openaire   +3 more sources

Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report

SAGE Open Medical Case Reports, 2023
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh, Elham Kabiri Naeini, Firouzeh Moeinzadeh, Azar Naimi   +3 more
doaj   +1 more source

Antiglomerular Basement Membrane Disease [PDF]

Seminars in Respiratory and Critical Care Medicine, 2014
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire   +5 more sources

Anti-Glomerular Basement Membrane Disease [PDF]

Journal of the American Society of Nephrology, 1999
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
openaire   +2 more sources

Rituximab for Anti–Glomerular Basement Membrane Disease [PDF]

Kidney International Reports, 2019
Anti–glomerular basement membrane (GBM) disease, characterized by antibodies against the NC1 domain of type IV collagen, presents with rapidly progressive glomerulonephritis that advances quickly to end-stage renal disease if not identified and treated in a timely fashion.
Jain, Rashmi, Dgheim, Hanna, Bomback, Andrew S.   +2 more
openaire   +2 more sources

Prognostic value of complement serum C3 level and glomerular C3 deposits in anti-glomerular basement membrane disease. [PDF]

Front Immunol, 2023
Caillard P, Vigneau C, Halimi JM, Hazzan M, Thervet E, Heitz M, Juillard L, Audard V, Rabant M, Hertig A, Subra JF, Vuiblet V, Guerrot D, Tamain M, Essig M, Lobbedez T, Quemeneur T, Legendre M, Ganea A, Peraldi MN, Vrtovsnik F, Daroux M, Makdassi R, Choukroun G, Titeca-Beauport D.   +24 more
europepmc   +2 more sources

Atypical anti-glomerular basement membrane disease [PDF]

Clinical Kidney Journal, 2015
Anti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs ...
Troxell, Megan L., Houghton, Donald C.
openaire   +2 more sources

Recurrent, atypical anti-glomerular basement membrane disease

Indian Journal of Nephrology, 2021
Anti-glomerular basement membrane disease (GBM) (Goodpasture's disease) typically presents with acute manifestations of rapidly progressive glomerulonephritis often accompanied by lung haemorrhage. Anti-GBM disease is usually monophasic. However, atypical presentations with indolent renal involvement are being increasingly recognized.
Jamboti, Jagadish S., Sinniah, Rajalingam, Dorsogna, Lloyd, Holmes, Christian   +3 more
openaire   +2 more sources

Rituximab in anti-glomerular basement membrane disease [PDF]

QJM, 2011
The role of rituximab has expanded beyond the treatment of non-Hodgkins lymphoma,1 to include successful management of rheumatoid arthritis,2 systemic lupus erythematosus,3 anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis4 and primary glomerulonephritis.5 Decrease incidence of side-effects or toxicity, coupled with clinical ...
Y, Shah, A, Mohiuddin, C, Sluman, I, Daryanani, T, Ledson, A, Banerjee, A, Crowe, P, McClelland   +7 more
openaire   +2 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source