Results 21 to 30 of about 33,810 (217)
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +1 more source
Antiglomerular Basement Membrane Disease [PDF]
Seminars in Respiratory and Critical Care Medicine, 2014 AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire +7 more sources
Recurrent, atypical anti-glomerular basement membrane disease
Indian Journal of Nephrology, 2021 Anti-glomerular basement membrane disease (GBM) (Goodpasture's disease) typically presents with acute manifestations of rapidly progressive glomerulonephritis often accompanied by lung haemorrhage. Anti-GBM disease is usually monophasic. However, atypical presentations with indolent renal involvement are being increasingly recognized.
Jamboti, Jagadish S. +3 more
openaire +2 more sources
Anti-glomerular basement membrane disease [PDF]
Kidney International, 2003 Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD +13 more
openaire +3 more sources
Anti-Glomerular Basement Membrane Disease [PDF]
Journal of the American Society of Nephrology, 1999 Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
openaire +2 more sources
Atypical anti-glomerular basement membrane disease [PDF]
Clinical Kidney Journal, 2015 Anti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs ...
Troxell, Megan L., Houghton, Donald C.
openaire +2 more sources
SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report
BMC Nephrology, 2021 Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage.
Alexander Winkler +5 more
doaj +1 more source
Anti-glomerular basement membrane disease
Ibnosina Journal of Medicine and Biomedical Sciences, 2011 Anti–glomerular basement membrane (anti-GBM) disease is a rare autoimmune disorder characterized by rapidly progressive glomerulonephritis (RPGN) with diffuse crescentic formation on renal biopsy, and it is a well-characterized cause of glomerulonephritis.
Sergey Brodsky, Anjali Satoskar
+6 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Anti–Glomerular Basement Membrane Disease
Rheumatic Disease Clinics of North America, 2018 Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune small vessel vasculitis characterized by autoreactivity to antigens in type IV collagen chains expressed in glomerular and alveolar basement membrane. The detection of circulating anti-GBM antibodies, which are shown to be directly pathogenic, is central to disease diagnosis ...
Gulati, K, McAdoo, SP
openaire +4 more sources