Results 31 to 40 of about 7,623,830 (208)
Anti-Glomerular Basement Membrane Disease [PDF]
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
openaire +2 more sources
Rituximab for Anti–Glomerular Basement Membrane Disease [PDF]
Anti–glomerular basement membrane (GBM) disease, characterized by antibodies against the NC1 domain of type IV collagen, presents with rapidly progressive glomerulonephritis that advances quickly to end-stage renal disease if not identified and treated in a timely fashion.
Jain, Rashmi +2 more
openaire +2 more sources
Recurrent, atypical anti-glomerular basement membrane disease
Anti-glomerular basement membrane disease (GBM) (Goodpasture's disease) typically presents with acute manifestations of rapidly progressive glomerulonephritis often accompanied by lung haemorrhage. Anti-GBM disease is usually monophasic. However, atypical presentations with indolent renal involvement are being increasingly recognized.
Jamboti, Jagadish S. +3 more
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Atypical anti-glomerular basement membrane disease [PDF]
Anti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs ...
Troxell, Megan L., Houghton, Donald C.
openaire +2 more sources
Rituximab in anti-glomerular basement membrane disease [PDF]
The role of rituximab has expanded beyond the treatment of non-Hodgkins lymphoma,1 to include successful management of rheumatoid arthritis,2 systemic lupus erythematosus,3 anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis4 and primary glomerulonephritis.5 Decrease incidence of side-effects or toxicity, coupled with clinical ...
Y, Shah +7 more
openaire +2 more sources
SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report
Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage.
Alexander Winkler +5 more
doaj +1 more source
Anti-Glomerular Basement Membrane Disease in Association with Pembrolizumab Treated with Rituximab in Addition to Standard Care: A Case Report. [PDF]
Introduction: Immune checkpoint inhibitors have significantly improved the prognosis of patients with certain malignancies; however, they can also be associated with diverse autoimmune organ toxicities, including those affecting the kidney.
Lopez T, Srikantharajah M, McAdoo S.
europepmc +2 more sources
Permselectivity of the glomerular wall examined with iron compound tracer [PDF]
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core +1 more source
Anti-Glomerular Basement Membrane Disease and Renal Obstruction
Dr. Figueiredo Cátia R. +2 more
doaj +3 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source

