Anti-glomerular basement membrane disease-treatment standard. [PDF]
Nephrol Dial TransplantABSTRACT We review the current standards of treatment and discuss novel developments in the pathophysiology, diagnosis, outcome prediction and management of anti-glomerular basement membrane (anti-GBM) disease. Anti-GBM disease is a unique form of small vessel vasculitis affecting the glomerular and pulmonary capillaries. It is caused
McAdoo SP, Pusey CD.
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Anti-glomerular basement membrane disease [PDF]
Kidney International, 2003 Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD +13 more
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Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
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The Prevalence and Characteristics of Circulating IgA Anti-Glomerular Basement Membrane Autoantibodies in Anti-Glomerular Basement Membrane Disease. [PDF]
Kidney Int Rep, 2023 In some cases, immunoglobulin (IgA)-mediated antiglomerular basement membrane (anti-GBM) disease has been reported. Whether circulating IgA anti-GBM antibodies affect the clinico-pathologic characteristics and outcome of typical anti-GBM disease deserves further study.Circulating IgA anti-α3(IV)NC1 antibodies were examined by enzyme-linked ...
Yang XF +7 more
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Anti-Glomerular Basement Membrane Disease [PDF]
Journal of the American Society of Nephrology, 1999 Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
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Antiglomerular Basement Membrane Disease [PDF]
Seminars in Respiratory and Critical Care Medicine, 2014 AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
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A Rare Case of Atypical Anti-glomerular Basement Membrane Disease. [PDF]
Cureus, 2023 Anti-glomerular basement membrane (Anti-GBM) disease is a severe form of glomerulonephritis (GN) that predominantly impacts individuals aged 20 to 70. It arises from the presence of circulating antibodies that specifically target an antigen inherent to the basement membranes of glomerular and alveolar structures. A unique subset within this category is
Gupta S +8 more
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Estimating Prognosis in Anti-Glomerular Basement Membrane Disease. [PDF]
J Am Soc Nephrol, 2023 Glassock RJ.
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Prognostic value of complement serum C3 level and glomerular C3 deposits in anti-glomerular basement membrane disease. [PDF]
Front Immunol, 2023 Caillard P +24 more
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Rituximab for Anti–Glomerular Basement Membrane Disease [PDF]
Kidney International Reports, 2019 Anti–glomerular basement membrane (GBM) disease, characterized by antibodies against the NC1 domain of type IV collagen, presents with rapidly progressive glomerulonephritis that advances quickly to end-stage renal disease if not identified and treated in a timely fashion.
Jain, Rashmi +2 more
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