Results 51 to 60 of about 7,623,830 (208)

Atypical Goodpasture’s disease: a clinical case report and literature review [PDF]

Терапевтический архив, 2018
Goodpasture’s disease (anti-GBM disease) is a rare small vessels vasculitis characterized by the presence of autoantibodies directed against the glomerular basement membrane (GBM) and alveolar basement membrane.
M L Bulanova, D V Potapov, N M Bulanov, L V Lysenko(Kozlovskaya)   +3 more
doaj   +1 more source

Anti-glomerular basement membrane disease in HLA-identical non-twin siblings

Nefrología (English Edition), 2022
Anti glomerular basement membrane disease (AGBM) is an autoinmune disorder characterised by the presence of anti-glomerular basement membrane (Anti-GBM) antibodies, alveolar hemorrhage, necrotizing glomerulonephritis, and linear deposition of ...
Paz Castro Fernández, María Dolores Sánchez de la Nieta García, Minerva Arambarri Segura, Lucía González López, Diego Sidel Tambo, Esperanza Moral Berrio, Guillermo Ferrer García, Agustín Carreño Parrilla, Alberto Martínez Calero, Ana Sánchez Fructuoso, Carmen Vozmediano Poyatos   +10 more
doaj   +1 more source

Monotypic IgG1-kappa Atypical Anti-Glomerular Basement Membrane Nephritis: A Case Report

Case Reports in Nephrology and Dialysis, 2019
Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by autoantibodies against the glomerular basement membrane. Atypical anti-GBM nephritis is clinically less aggressive and characterized by the absence of circulating
Maxim Olivier, Harold Watson, Danielle Lee, Viresh Mohanlal, Mario Madruga, Steven Carlan   +5 more
doaj   +1 more source

Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity [PDF]

, 2005
When purified under rigorous conditions, some murine anti-double-stranded-DNA (anti-dsDNA) antibodies actually bind chromatin rather than dsDNA. This suggests that they may actually be antinucleosome antibodies that only appear to bind dsDNA when they ...
Lambrianides, A, Rahman, A, Anisur Rahman, Isenberg, DA, Mason, LJ, David S Latchman, Lesley J Mason, Manson, JJ, Latchman, DS, Jessica J Manson, David A Isenberg, Joanna D Haley, Haley, JD, Anastasia Lambrianides   +13 more
core   +1 more source

Membranous nephropathy followed by anti-glomerular basement disease: A case report and review of clinical presentation and treatment

SAGE Open Medical Case Reports, 2018
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer, Matthias Martin Gaida, Rüdiger Waldherr, Christian Nusshag, Florian Kälble, Martin Zeier   +5 more
doaj   +1 more source

A case of bizarre posttransplant anti-glomerular basement membrane disease

Central European Journal of Immunology, 2019
The non-collagenous (NC1) domain of 3 and 5 chains of type IV collagen are eminent targets of abnormal immune response in anti-glomerular basement membrane (anti-GBM) disease, which can be diagnosed by the presence of strong linear IgG staining along ...
Anna Olewicz-Gawlik, Jan Żeromski, Monika Świerczewska, Ilona Idasiak-Piechocka, Magdalena Pawlik, Dorota Sikorska, Husam Samara, Andrzej Oko, Jan Sikora, Grzegorz Dworacki   +9 more
doaj   +1 more source

Pembrolizumab-Induced Anti-GBM Glomerulonephritis: A Case Report

Kidney Medicine, 2023
Immune checkpoint inhibitors are known to have a wide range of autoimmune toxicities, such as acute interstitial nephritis. Immunotherapy induced glomerulonephritis has been described, but anti-glomerular basement membrane disease (anti-GBM) is rarely ...
Nidal El Yamani, Gabrielle Cote, Julie Riopel, Nicolas Marcoux, Fabrice Mac-Way, David Philibert, Mohsen Agharazii   +6 more
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Anti-glomerular basement membrane disease associated with thin basement membrane nephropathy

Medicine, 2021
Abstract Rationale: Simultaneous occurrence of anti-glomerular basement membrane (anti-GBM) disease and thin basement membrane nephropathy (TBMN), both of which invade the type IV collagen subunits, is very rare. Here, we present the case of a 20-year-old male patient diagnosed with both anti-GBM disease and TBMN upon
Chi Young Jung, Sun-Jae Lee, Min-Kyung Kim, Dong Jik Ahn, In Hee Lee   +4 more
openaire   +2 more sources