Results 41 to 50 of about 22,460 (165)

Advances in the Genetics of Anti-Glomerular Basement Membrane Disease [PDF]

American Journal of Nephrology, 2010
Anti-glomerular basement membrane (GBM) disease is a rare but lethal autoimmune disorder. Over the past few years, the nature of the autoantigen and its epitopes has been defined, as well as the possible pathogenic role played by environmental factors, and by cellular and humoral immunity.
Xu-Jie, Zhou, Ji-Cheng, Lv, Ming-Hui, Zhao, Hong, Zhang   +3 more
openaire   +2 more sources

Anti-glomerular Basement Membrane Disease with Antiphospholipid Syndrome

Internal Medicine, 2021
A 48-year-old woman presented with a fever, microscopic hematuria, proteinuria, and rapid deterioration of the renal function. Pulmonary alveolar hemorrhaging and a high level of anti-glomerular basement membrane (GBM) antibodies (700 IU/mL) were observed.
Torigoe, Miki, Obata, Yoko, Kitamura, Mineaki, Hara, Shigeo, Fukuoka, Junya, Nishino, Tomoya   +5 more
openaire   +3 more sources

Anti-glomerular basement membrane disease in HLA-identical non-twin siblings

Nefrología (English Edition), 2022
Anti glomerular basement membrane disease (AGBM) is an autoinmune disorder characterised by the presence of anti-glomerular basement membrane (Anti-GBM) antibodies, alveolar hemorrhage, necrotizing glomerulonephritis, and linear deposition of ...
Paz Castro Fernández, María Dolores Sánchez de la Nieta García, Minerva Arambarri Segura, Lucía González López, Diego Sidel Tambo, Esperanza Moral Berrio, Guillermo Ferrer García, Agustín Carreño Parrilla, Alberto Martínez Calero, Ana Sánchez Fructuoso, Carmen Vozmediano Poyatos   +10 more
doaj   +1 more source

Monotypic IgG1-kappa Atypical Anti-Glomerular Basement Membrane Nephritis: A Case Report

Case Reports in Nephrology and Dialysis, 2019
Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by autoantibodies against the glomerular basement membrane. Atypical anti-GBM nephritis is clinically less aggressive and characterized by the absence of circulating
Maxim Olivier, Harold Watson, Danielle Lee, Viresh Mohanlal, Mario Madruga, Steven Carlan   +5 more
doaj   +1 more source

Membranous nephropathy followed by anti-glomerular basement disease: A case report and review of clinical presentation and treatment

SAGE Open Medical Case Reports, 2018
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer, Matthias Martin Gaida, Rüdiger Waldherr, Christian Nusshag, Florian Kälble, Martin Zeier   +5 more
doaj   +1 more source

A case of bizarre posttransplant anti-glomerular basement membrane disease

Central European Journal of Immunology, 2019
The non-collagenous (NC1) domain of 3 and 5 chains of type IV collagen are eminent targets of abnormal immune response in anti-glomerular basement membrane (anti-GBM) disease, which can be diagnosed by the presence of strong linear IgG staining along ...
Anna Olewicz-Gawlik, Jan Żeromski, Monika Świerczewska, Ilona Idasiak-Piechocka, Magdalena Pawlik, Dorota Sikorska, Husam Samara, Andrzej Oko, Jan Sikora, Grzegorz Dworacki   +9 more
doaj   +1 more source

Pembrolizumab-Induced Anti-GBM Glomerulonephritis: A Case Report

Kidney Medicine, 2023
Immune checkpoint inhibitors are known to have a wide range of autoimmune toxicities, such as acute interstitial nephritis. Immunotherapy induced glomerulonephritis has been described, but anti-glomerular basement membrane disease (anti-GBM) is rarely ...
Nidal El Yamani, Gabrielle Cote, Julie Riopel, Nicolas Marcoux, Fabrice Mac-Way, David Philibert, Mohsen Agharazii   +6 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Anti-glomerular basement membrane disease associated with thin basement membrane nephropathy

Medicine, 2021
Abstract Rationale: Simultaneous occurrence of anti-glomerular basement membrane (anti-GBM) disease and thin basement membrane nephropathy (TBMN), both of which invade the type IV collagen subunits, is very rare. Here, we present the case of a 20-year-old male patient diagnosed with both anti-GBM disease and TBMN upon
Chi Young Jung, Sun-Jae Lee, Min-Kyung Kim, Dong Jik Ahn, In Hee Lee   +4 more
openaire   +2 more sources