Results 21 to 30 of about 3,164,975 (245)

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Frequency of active HCV infection among anti-HCV positive patients in selected districts of Khyber Pakhtunkhwa, Pakistan [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2013
Objective: The objective of this study was to determine frequency of active HCV infection among confirmed anti-HCV positive subjects of KPK in order to help the infected subjects decide about anti-viral treatment options.Methods: Blood samples (3075 ...
Sajid Ali   +3 more
doaj   +2 more sources

Estimating the scale of chronic hepatitis C virus infection in the EU/EEA: a focus on migrants from anti-HCV endemic countries

open access: yesBMC Infectious Diseases, 2018
BackgroundIncreasing the proportion diagnosed with and on treatment for chronic hepatitis C (CHC) is key to the elimination of hepatitis C in Europe. This study contributes to secondary prevention planning in the European Union/European Economic Area (EU/
A. Falla   +4 more
semanticscholar   +1 more source

Identification of novel neutralizing determinants for protection against HCV

open access: yesHepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua   +12 more
wiley   +1 more source

Prenatal hepatitis C screening, diagnoses, and follow-up testing in British Columbia, 2008-2019.

open access: yesPLoS ONE, 2020
ObjectiveCurrent guidelines in British Columbia recommend prenatal screening for hepatitis C antibodies (anti-HCV) if risk factors are present. We aimed to estimate frequency of prenatal anti-HCV testing, new diagnoses, repeated and follow-up testing ...
Margo E Pearce   +15 more
doaj   +1 more source

A study based on four immunoassays: Hepatitis C virus antibody against different antigens may have unequal contributions to detection

open access: yesVirology Journal, 2021
Background All commercial Hepatitis C virus antibody (anti-HCV) assays use a combination of recombinant antigens to detect antibody response. Antibody responses to individual antigenic regions (core, NS3/4 and NS5) used in assays have not been ...
Xinyi Jiang   +6 more
doaj   +1 more source

Evaluation of the automated fluorescent immunoassay system anti-hepatitis C virus assay for the detection of hepatitis C virus infection

open access: yesGlobal Journal of Transfusion Medicine, 2019
Introduction: Hepatitis C has emerged as a fatal epidemic in the country in the past two decades. One of the major risk factors remains unsafe blood transfusions.
Usman Waheed   +8 more
doaj   +1 more source

Changing epidemiology and viral interplay of hepatitis B, C and D among injecting drug user-dominant prisoners in Taiwan

open access: yesScientific Reports, 2021
The spreading of viral hepatitis among injecting drug users (IDU) is an emerging public health concern. This study explored the prevalence and the risks of hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV) among IDU-dominant ...
Ming-Ying Lu   +26 more
doaj   +1 more source

Evaluation of a New Anti-HCV-Assay Kit for Anti-HCV Screening in Early Childhood.

open access: yesThe Tohoku Journal of Experimental Medicine, 1999
Sera of 20 children falsely identified as positive for hepatitis C virus antibody (Anti-HCV) by a second generation anti-HCV-assay kit (Imucheck-HCV Ab "Kokusai") were re-tested using a new third generation anti-HCV-assay kit (Imucheck x F-HCV C50 Ab "Kokusai").
Sugiyama, Kohachiro   +8 more
openaire   +3 more sources

Comparison of HCV core antigen and anti-HCV with HCV RNA results.

open access: yesAfrican Health Sciences, 2015
BACKGROUND The measurement of anti-HCV antibodies using immunological methods and the confirmation of viral nuclear acid based on molecular methods is important in diagnosis and follow-up of the HCV infection.
Cicioğlu Arıdoğan Buket   +4 more
semanticscholar   +1 more source

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