Results 61 to 70 of about 3,182,211 (266)

Preclinical evaluation of an anti-HCV miRNA cluster for treatment of HCV infection.

Molecular Therapy, 2013
We developed a strategy to treat hepatitis C virus (HCV) infection by replacing five endogenous microRNA (miRNA) sequences of a natural miRNA cluster (miR-17-92) with sequences that are complementary to the HCV genome. This miRNA cluster (HCV-miR-Cluster
X. Yang, K. Marcucci, X. Anguela, L. Couto   +3 more
semanticscholar   +1 more source

Orthotopic liver transplantation in human-immunodeficiency-virus-positive patients in Germany [PDF]

, 2012
Objectives: This summary evaluates the outcomes of orthotopic liver transplantation (OLT) of HIV-positive patients in Germany. Methods: Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July ...
Anadol, Evrim, Beckebaum, Susanne, Berg, C., Bickel, Markus, Ganten, Tom M., Hitzenbichler, Florian, Kalff, Jörg C., Kittner, Jens Martin, Manekeller, Steffen, Paul, Andreas, Radecke, Klaus, Rockstroh, Jürgen, Sauerbruch, Tilman, Spengler, Ulrich, Stoll, Matthias, Zoufaly, Alexander   +15 more
core   +2 more sources

Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]

, 2017
In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela, Corach, Daniel, Flichman, Diego Martin, Hulaniuk, María L., Trinks, Julieta   +4 more
core   +1 more source

Hepatitis C virus (HCV) micro-elimination in the hospital setting: The results of the HCV Caserta hospital project

Journal of Infection and Public Health, 2022
Background: In the present study we evaluated the efficacy of an innovative model of HCV micro-elimination in a hospital setting in an area of high HCV prevalence.
Vincenzo Messina, Mariantonietta Pisaturo, Loredana Alessio, Antonio Russo, Elena Tripaldelli, Arnolfo Petruzziello, Angela Annecchiarico, Maria Rosaria Romano, Paolo Maggi, Nicola Coppola   +9 more
doaj   +1 more source

Performance study of the automated immunoassay test anti-hepatitis C virus VIDAS® for the qualitative detection of antibodies anti-hepatitis C virus

Microbiologia Medica, 2016
Background and aims: Hepatitis C virus (HCV) represents a major worldwide public health problem requiring global action for the diagnosis, treatment and prevention of this infection.
Sara Salvetti, Federica Lavinia, Iolanda Montenora   +2 more
doaj   +1 more source

Longitudinal study of a human drug-induced model of autoantibody to cytoplasmic rods/rings following HCV therapy with ribavirin and interferon-α. [PDF]

PLoS ONE, 2012
A novel pattern in the indirect immunofluorescence antinuclear antibody assay on HEp-2 cells (IIF-HEp-2) characterized by cytoplasmic rods and rings (RR) was reported in HCV patients, but stringent disease specificity studies and longitudinal analysis ...
Gerson Dierley Keppeke, Eunice Nunes, Maria Lucia Gomes Ferraz, Eduardo Antônio Benedito Silva, Celso Granato, Edward K L Chan, Luís Eduardo C Andrade   +6 more
doaj   +1 more source

Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models [PDF]

, 2010
Chimpanzees represent the only animal model for studies of the natural history of hepatitis C virus (HCV). To generate virus stocks of important HCV variants, we infected chimpanzees with HCV strains of genotypes 1-6 and determined the infectivity titer ...
Bukh, Jens, Eder, Gerald, Engle, Ronald E, Feinstone, Stephen M, Govindarajan, Sugantha, Krawczynski, Krzysztof, Leroux-Roels, Geert, Meuleman, Philip, Miller, Roger H, Purcell, Robert H, Satterfield, William C, Tellier, Raymond   +11 more
core   +1 more source

Anti-HCV prevalence in the general population of Lithuania

Medical Science Monitor, 2012
Summary Background The aim of this study was to assess risk factors for HCV acquisition and prevalence of anti-HCV in the general population of Lithuania.
V. Liakina, J. Valantinas
semanticscholar   +1 more source

Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV

Virology Journal, 2011
Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by
N. Khan, Ijaz Ali, N. Ahmad, A. Iqbal, Latif U Rehman, I. Munir, M. Rehman, Sanaullah Khan, Sajid Ali, Lubna Siddique, Z. Swati   +10 more
semanticscholar   +1 more source

Hepatites pós-transfusionais na cidade de Campinas, SP, Brasil: II. Presença dos anticorpos anti-HBc e anti-HCV em candidatos a doadores de sangue e ocorrência de hepatites pós-transfusionais pelo vírus C nos receptores de sangue ou derivados Post-transfusional hepatitis in the city of Campinas, SP, Brazil: II- Presence of anti-HBc and anti-HCV antibodies in blood donors and occurrence of post-transfusional hepatitis C virus in recipients of blood or derivates

Revista do Instituto de Medicina Tropical de São Paulo, 1993
Pesquisamos os anticorpos anti-HBc e anti-HCV em amostras de soros provenientes de 799 candidatos a doadores, que tiveram suas unidades de sangue ou derivados transfundidas a 111 receptores. O anti-HBc e o anti-HCV foram reagentes, em respectivamente 9 e
Fernando Lopes Gonçales Júnior, Rogério de Jesus Pedro, Luiz Jacintho da Silva, Raquel Silveira Bello Stucchi Boccato, Neiva Sellan Lopes Gonçales   +4 more
doaj   +1 more source