Results 161 to 170 of about 354,830 (305)

Sulfanylbenzamides with Unique Side Chains to Improve Metabolic Stability, Pharmacokinetics, and Anti-HIV Activity. [PDF]

J Med Chem
Robello M, Lehman RF, Appella DH.
europepmc   +1 more source

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

Macromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt, Anna‐Lena Ziegler, Florian T. Kaps, Laura J. Rosenberger, Matthias Bros, Holger Frey, Robert Luxenhofer   +6 more
wiley   +1 more source

Anti-HIV and Antimicrobial Activity of 7-Hydrazino-8-hydroxyquinoline-Based Aromatic Hydrazones. [PDF]

Int J Mol Sci
Kozmenko YV, Khisamov MM, Revtovich SV, Korolev SP, Sherman DK, Spiridonov VV, Kalnina LB, Valuev-Elliston VT, Gottikh MB, Kochetkov SN, Zemskaya AS, Solyev PN.   +11 more
europepmc   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies. [PDF]

Nat Commun
Fuchs SP, Mondragon PG, Zabizhin R, Tomer S, Wang L, Cook E, Dudley DM, Weisgrau KL, Furlott J, Coonen J, Alexander E, Xie J, Gao G, Termini JM, Martinez-Navio JM, Zhen A, Desrosiers RC.   +16 more
europepmc   +1 more source

International Registry of NKX2‐1‐Related Disorders: Clinical, Genetic, and Imaging Perspectives

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders result from heterozygous variants in NKX2‐1, a gene crucial for brain, lung, and thyroid development. Although movement disorders, hypothyroidism, and neonatal respiratory distress are recognized, the full phenotype and genotype–phenotype relationships remain incompletely defined.
Laia Nou‐Fontanet, Claudia Ravelli, Lydie Burglen, Sol Balsells Mejia, Angel Valls‐Villalba, Elies Roman Schiffels, Alice Innocenti, Beatriz Villafuerte, Ainara Salazar‐Villacorta, Vicente Quiroz, Andrea Sariego Jamardo, Giulia Bonato, Asun Díaz‐Gomez, Alexandra Afenjar, Catheline Vilain, Patricia Dumke da Silva Möller, Deyanira Garcia‐Navas Nuñez, Magdalena Krygier, Maria Judit Molnar, Łukasz Milanowski, Katrin Õunap, Micaela Pauni, Patricia Vega, Raphael Borie, Milena Villamil‐Osorio, Sanem Yilmaz, Dénes Zádori, Marta Zawadzka, Tahsin Stefan Barakat, Sebastian Neuens, Daniel de Natera‐de Benito, Dídac Casas‐Alba, Luca Soliani, Claudio M. de Gusmao, Giacomo Garone, Nicola Specchio, Miryam Carecchio, José C. Moreno, Francesca Magrinelli, Kailash P. Bhatia, Darius Ebrahimi‐Fakhari, Claudia Castiglioni, Manju Ann Kurian, João Nuno Carvalho, Roser Pons, Emmanuel Roze, Diane Doummar, Juan Darío Ortigoza‐Escobar   +47 more
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

New Advances in Anti-HIV-1 Strategies Targeting the Assembly and Stability of Capsid Protein. [PDF]

Int J Mol Sci
Zhang C, Li B, Li J, Zhang H, Wu Y.
europepmc   +1 more source

Efficient One‐Pot Synthesis of Benzothiazole Compounds From Vinamidinium Salts

ChemistryOpen, EarlyView.
A catalyst‐free one‐pot reaction of vinamidinium salts with benzothiazole hydrazines efficiently produces 1,3‐bis((3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)propan‐2‐ol (BBTA) and 1‐((1Z,3E)‐1‐(dimethylamino)‐3‐(((Z)‐3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)prop‐1‐en‐2‐yl)pyridin‐1‐ium (DMBT) derivatives.This simple method ...
Zeinab khosravi, Abdolmohammad Mehranpour, Mohammad Reza Mohammadizadeh, Genta Kojya, Satoru Arimitsuc   +4 more
wiley   +1 more source

J3ExoA: A Novel Anti-HIV Immunotoxin Fusion of Anti-Gp120 J3VHH and PE38 Fragment of <i>Pseudomonas</i> Exotoxin A. [PDF]

Pharmaceuticals (Basel)
Pincus SH, Luo K, Peters T, Gordy JT, Cole FM, Klug G, Ober K, Marcotte TK, Markham RB.   +8 more
europepmc   +1 more source