Results 161 to 170 of about 3,688,101 (379)

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]

, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I., Aubin, K., Borrow, P., Cornforth, D., Holuigue, S., Jones, N.A., McKnight, A., Newton, P., Pellegrino, P., Williams, I., Wong, M.   +10 more
core  

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic

Nature Medicine, 2019
M. Caskey, F. Klein, M. Nussenzweig
semanticscholar   +1 more source

Occult Hepatitis B virus infection among HIV negative and positive isolated anti-HBc individuals in eastern Ethiopia [PDF]

, 2020
Desalegn Admassu Ayana, Andargachew Mulu, Adane Mihret, Berhanu Seyoum, Abraham Aseffa, Rawleigh Howe   +5 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Stimuli-Sensitive Thiolated Hyaluronic Acid Based Nanofibers: Synthesis, Preclinical Safety And in vitro Anti-HIV Activity

, 2016
Vivek Agrahari, Jianing Meng, Miezan J. M. Ezoulin, Ibrahima Youm, Daniel C. Dim, Agostino Molteni, Wei‐Ting Hung, Lane K. Christenson, Bi‐Botti C. Youan   +8 more
openalex   +2 more sources

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117. [PDF]

, 2018
A clinical trial was performed to evaluate 3BNC117, a potent anti-HIV-1 antibody, in infected individuals during suppressive antiretroviral therapy and subsequent analytical treatment interruption (ATI).
Barton, John P, Belblidia, Shiraz A, Burke, Leah, Butler, Allison L, Caskey, Marina, Cohen, Yehuda Z, Dizon, Juan P, Gulick, Roy M, Jankovic, Mila, Krassnig, Lisa, Lorenzi, Julio CC, Lu, Ching-Lan, Mendoza, Pilar, Millard, Katrina, Nussenzweig, Michel C, Oliveira, Thiago Y, Pai, Joy, Seaman, Michael S, Shimeliovich, Irina, Sleckman, Christopher, Witmer-Pack, Maggi   +20 more
core   +1 more source