Results 241 to 250 of about 354,830 (305)
Preparation of a Key Intermediate En Route to the Anti-HIV Drug Lenacapavir. [PDF]
J Org ChemCaravez JC +4 more
europepmc +1 more source
Prodrug Strategy Extends the Use of Anti-HIV Sulfanylbenzamides for Application In Vivo. [PDF]
ACS Pharmacol Transl SciRobello M +5 more
europepmc +1 more source
Microwave-assisted synthesis of a zirconium-based MOF as an efficient catalyst for one-pot synthesis of xanthene derivatives: <i>in silico</i> study as a potential anti-HIV RNA. [PDF]
RSC AdvAlsalhi MS +5 more
europepmc +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Magí Brufau‐Cochs +7 more
wiley +1 more source
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Bioinformatics-assisted anti-HIV therapy
Nature Reviews Microbiology, 2006Highly active antiretroviral therapy (HAART), in which three or more drugs are given in combination, has substantially improved the clinical management of HIV-1 infection. Still, the emergence of drug-resistant variants eventually leads to therapy failure in most patients.
Thomas Lengauer, Tobias Sing
exaly +4 more sources
Molecular Biotechnology, 1997
HIV is an RNA virus that replicates intracellularly through various RNA intermediates. Several of these can be targeted by ribozymes (catalytic RNA molecules), and a number of investigators, including this group, have demonstrated the ability of ribozymes to suppress HIV replication in this way.
L Q, Sun +3 more
openaire +2 more sources
HIV is an RNA virus that replicates intracellularly through various RNA intermediates. Several of these can be targeted by ribozymes (catalytic RNA molecules), and a number of investigators, including this group, have demonstrated the ability of ribozymes to suppress HIV replication in this way.
L Q, Sun +3 more
openaire +2 more sources
Current Protein & Peptide Science, 2004
The cyclotides are a recently discovered, structurally unique family of bioactive plant peptides. Their discovery spawned a series of structural analyses, synthetic efforts, and studies to define the biosynthesis and biological properties of these novel peptide metabolites.
Kirk R, Gustafson +2 more
openaire +2 more sources
The cyclotides are a recently discovered, structurally unique family of bioactive plant peptides. Their discovery spawned a series of structural analyses, synthetic efforts, and studies to define the biosynthesis and biological properties of these novel peptide metabolites.
Kirk R, Gustafson +2 more
openaire +2 more sources
Expert Opinion on Emerging Drugs, 2005
There are now exactly 20 anti-HIV drugs licenced (approved) for clinical use, and > 30 anti-HIV compounds under (pre)clinical development. The licensed anti-HIV drugs fall into five categories: nucleoside reverse transcriptase inhibitors (NRTIs: zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine); nucleotide reverse ...
openaire +2 more sources
There are now exactly 20 anti-HIV drugs licenced (approved) for clinical use, and > 30 anti-HIV compounds under (pre)clinical development. The licensed anti-HIV drugs fall into five categories: nucleoside reverse transcriptase inhibitors (NRTIs: zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine); nucleotide reverse ...
openaire +2 more sources