Results 251 to 260 of about 3,688,101 (379)

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

Zinc Complexes of Cationic Ammonium Phenyl and Methylpyridinium Porphyrins Display Synergistic Anti-HIV‑1 and Broad-Spectrum Antibacterial Activity. [PDF]

ACS Omega
Sharma D, Rai M, Das N, Kapavarapu RK, Pandey P, Gaur R, Sengupta D.   +6 more
europepmc   +1 more source

Periodontitis in patients with severe erectile dysfunction undergoing penile prosthesis implantation: Clinical and immunohistochemical study

Journal of Periodontology, EarlyView.
Abstract Background The relationship between periodontitis and erectile dysfunction (ED) has been poorly documented in Caucasian populations, particularly severe ED (SED) requiring penile prostheses. This study aimed to evaluate the association between periodontitis and SED in patients undergoing penile prosthesis implantation, and to identify clinical
Miguel Ángel Arrabal‐Polo, Ana López‐Toruño, Antonio Magan‐Fernández, Miguel Arrabal Martin, Natividad Martín‐Morales, Eva Rosel, Manuel Bravo, Francisco O´Valle, Francisco Mesa   +8 more
wiley   +1 more source

Vaccine Induced Seroreactivity Following Administration of ALVAC-HIV/AIDSVAX®B/E Identified by Common Anti-HIV Test Kits and Algorithms in Thailand. [PDF]

Open Forum Infect Dis
Akapirat S, Serti E, Pitisutthithum P, Nitayaphan S, Chariyalertsak S, Eamsila C, Panjapornsuk P, Kleebmontha A, Chantakulkij S, Tongchanakarn B, Savadsuk H, Dhitavat J, Gurunathan S, Sinangil F, Crowell TA, Michael NL, Robb ML, Vasan S, O'Connell RJ, RV306 Study Group .   +19 more
europepmc   +1 more source

Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania [PDF]

, 2006
Omar JM Hamza, Mecky IN Matee, Elison N. M. Simon, Emil N. Kikwilu, Mainen J. Moshi, Ferdinand Mugusi, F.H.M. Mikx, Paul E. Verweij, André JAM van der Ven   +8 more
openalex   +1 more source

Isolated anal tuberculosis presenting as an anal fistula in an immunocompetent child

JPGN Reports, EarlyView.
Abstract Extra‐pulmonary tuberculosis accounts for less than 15% of all tuberculosis cases, while intestinal tuberculosis accounts for less than 1% of extra‐pulmonary forms of the disease. Abdominal organ involvement is more common, but extension to the ano‐perineal region is extremely rare.
Mariam Lagrine, Rabiy Elqadiry, Houda Nassih, Aicha Bourrahouat, Imane Ait Sab   +4 more
wiley   +1 more source

A pilot model of centralized anti-HIV-1 drug resistance testing with decentralized treatment in resource-limited settings. [PDF]

Glob Health Med
Nguyen TM, Tran GV, Pham TN, Matsumoto S, Nagai M, Tanuma J, Oka S, SATREPS project team.   +7 more
europepmc   +1 more source

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.

Proceedings of the National Academy of Sciences of the United States of America, 1999
M. Baba, Osamu Nishimura, N. Kanzaki, M. Okamoto, H. Sawada, Y. Iizawa, M. Shiraishi, Y. Aramaki, K. Okonogi, Y. Ogawa, Kanji Meguro, M. Fujino   +11 more
semanticscholar   +1 more source

Associations between health care access and posttraumatic stress disorder symptoms among rural and urban lesbian, gay, bisexual, transgender, and queer adults

Journal of Traumatic Stress, EarlyView.
Abstract Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) individuals experience elevated rates of trauma exposure, minority stress, and posttraumatic stress disorder (PTSD). Yet, research examining how geographic location and LGBTQ+ identity shape PTSD outcomes is scant, particularly studies considering structural facilitators and barriers ...
Emily A. Kenyon, Michelle A. Stage, Reina Kiefer, Mollie A. Ruben, Nicholas A. Livingston, Danielle S. Berke, Jillian C. Shipherd   +6 more
wiley   +1 more source

Combining an OSMAC approach and untargeted metabolomics to profile compounds exhibiting anti-HIV-1 activities in an endophytic fungus, Penicillium Rubens P03MB2. [PDF]

Sci Rep
Moloi N, Khumalo MC, Nxumalo WP, Mtambo SE, Mkhwanazi NP, Ndlovu SI.   +5 more
europepmc   +1 more source