Anti-HIV therapy: pipeline approaches and future directions [PDF]
, 2011 Human immunodeficiency virus (HIV), with about 30 million deaths and double infections (in developing countries), is an open challenge today for global scientists.
Lavkush Dwivedi, Mansi Shrivastava
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Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. [PDF]
, 2016 Identifying host immune determinants governing HIV transcription, latency and infectivity in vivo is critical to developing an HIV cure. Based on our recent finding that the host factor p21 regulates HIV transcription during antiretroviral therapy (ART),
Abdel-Mohsen, Mohamed +17 more
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Anti-HIV seropositivity among different group of patients; an observation from a secondary medical center in an endemic area of HIV infection [PDF]
Journal of Preventive Epidemiology, 2019 Human immunodeficiency virus (HIV) infection is an important medical problem worldwide. Since there is still no curative treatment, the good management for the HIV infected patient is necessary.
Pathum Sookaromdee, Viroj Wiwanitkit
doaj
Novel Antiretroviral Structures from Marine Organisms
Molecules, 2019 In spite of significant advancements and success in antiretroviral therapies directed against HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form and become reactivated under favorable conditions.
Karlo Wittine +3 more
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Dual-acting stapled peptides target both HIV-1 entry and assembly [PDF]
, 2013 Background: Previously, we reported the conversion of the 12-mer linear and cell-impermeable peptide CAI to a cell-penetrating peptide NYAD-1 by using an i,i + 4 hydrocarbon stapling technique and confirmed its binding to the C-terminal domain (CTD ...
Bhargava, P. +12 more
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Anti-HIV activity in cervical-vaginal secretions from HIV-positive and -negative women correlate with innate antimicrobial levels and IgG antibodies. [PDF]
PLoS ONE, 2010 We investigated the impact of antimicrobials in cervicovaginal lavage (CVL) from HIV(+) and HIV(-) women on target cell infection with HIV. Since female reproductive tract (FRT) secretions contain a spectrum of antimicrobials, we hypothesized that CVL ...
Mimi Ghosh +10 more
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Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production [PDF]
, 2014 © 2014 Pandit et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Al-Mozaini, MA +12 more
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Hepatitis C virus infection among injection drug users with and without human immunodeficiency virus co-infection. [PDF]
PLoS ONE, 2014 The aim of this study is to explore the prevalence of hepatitis C virus (HCV) infection among injection drug users (IDUs) with and without human immunodeficiency virus (HIV) infection in southern Taiwan.
Meng-Hsuan Hsieh +13 more
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Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
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Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]
, 2014 The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA +4 more
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