Results 31 to 40 of about 3,688,101 (379)

Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production [PDF]

, 2014
© 2014 Pandit et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Al-Mozaini, MA, Gajbhiye, R, Gopal, S, Idicula-Thomas, S, Kishore, U, Kulkarni, V, Madan, T, Pandit, H, Patil, A, Qaseem, AS, Sonawani, A, Warke, H, Yadav, AK   +12 more
core   +9 more sources

Antibacterial, Anti-HIV-1 Protease and Cytotoxic Activities of Aqueous Ethanolic Extracts from Combretum Adenogonium Steud. Ex A. Rich (Combretaceae). [PDF]

, 2012
\ud \ud Records have shown that Combretum adenogonium Steud. Ex A. Rich (Combretaceae) is used in traditional medicine systems of several tribes in Tanzania. This study focused on the investigation of antibacterial activity, anti-HIV-1 protease activity,
A Sartoratto, AO Maima, BN Meyer, DP Kisangau, Ester Innocent, GE Trease, GE Wickens, H Kolodziej, H Tsuchiya, J Koudou, JAO Ojewole, JB Harborne, JN Eloff, JN Eloff, JO Kokwaro, JR Litchfield Jr, K Batawila, K Inngjerdingen, LJ McGaw, MJ Moshi, MM Iwu, NM Useh, Novatus F Mushi, P Fyhrquist, P Fyhrquist, P Fyhrquist, P Masoko, S Maregesi, S Tewtrakul, S Tewtrakul, SC Chhabra, SM Maregesi, SM Maregesi, Supinya Tewtrakul, Zakaria H Mbwambo   +34 more
core   +3 more sources

Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model

Science Translational Medicine, 2019
Multispecific duoCAR-T cells potently suppress HIV infection in a humanized mouse model. Driving a new HIV therapy forward CAR T cells, which are now associated with cancer therapy, were previously investigated as a treatment for HIV almost 30 years ago.
K. Anthony-Gonda, A. Bardhi, A. Ray, Nina C Flerin, Mengyan Li, Wei-zao Chen, C. Ochsenbauer, J. Kappes, W. Krueger, A. Worden, D. Schneider, Zhongyu Zhu, R. Orentas, D. Dimitrov, H. Goldstein, B. Dropulić   +15 more
semanticscholar   +1 more source

Kan vericilerde HBsAg, anti-HCV, anti-HIV ve Sifilis seroprevalansı

Sakarya Tıp Dergisi, 2011
Bu çalışmada Afyon Kocatepe Üniversitesi Tıp Fakültesi Kan Merkezi'ne başvuran donörlerde HBsAg, anti-HCV, anti-HIV 1/2 ve RPR seroprevalansının tespiti ve oranların yıllara ve cinsiyete göre dağılımının belirlenmesi amaçlanmıştır.
Mustafa Altındiş, Raike Kalaycı, Savaş Aslan   +2 more
doaj   +1 more source

Clinical diagnostic accuracy of the HIV rapid test ACCU-TELL anti-HIV 1 + 2 in sub-Saharan African region. [PDF]

BMC Infect Dis
M Pirah V, Mbomo S, Mintsa A, Emane AA, Chirack NOD, Ghestin NMT, Lorine QE, Mahmoudou S, Siawaya JFD, Essone PN.   +9 more
europepmc   +3 more sources

Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity

Molecules, 2018
Background: Despite the progress achieved by anti-retroviral drug research in the last decades, the discovery of novel compounds endowed with selective antiviral activity and reduced side effects is still a necessity.
C. Saturnino, F. Grande, S. Aquaro, A. Caruso, Domenico Iacopetta, M. Bonomo, P. Longo, D. Schols, M. Sinicropi   +8 more
semanticscholar   +1 more source

Presence of IgG anti-gp160/120 antibodies confers higher HIV capture capacity to erythrocytes from HIV-positive individuals. [PDF]

PLoS ONE, 2012
BACKGROUND: HIV binding has been demonstrated in erythrocytes from HIV-positive and HIV-negative individuals. However, the presence of immunoglobulins G anti-HIV (IgG anti-HIV) in erythrocytes from HIV-positive individuals is still to be elucidated ...
Maria Noé Garcia, Maria Sol dos Ramos Farias, Lucia Fazzi, Daniel Grasso, Roberto Daniel Rabinovich, Maria Mercedes Ávila   +5 more
doaj   +1 more source

Structure-Based Discovery and Characterization of a Preclinical Drug Candidate for the Treatment of HIV-1 Infection

Viruses, 2022
HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) area key component of the current HIV-1 combination drug regimens. Although they exhibit potent anti-HIV-1 activity and modest toxicity, the emergence of mutant strains limits their ...
Dongwei Kang, Jinxuan Yang, Lingjin Kong, Ronghua Luo, Xusheng Huang, Tao Zhang, Mengdi Ma, Da Feng, Zhao Wang, Hao Fang, Peng Zhan, Yongtang Zheng, Xinyong Liu   +12 more
doaj   +1 more source

Modern anti-HIV therapy

Swiss Medical Weekly, 2001
Highly active antiretroviral therapies (HAART), usually consisting of two nucleoside reverse transcriptase inhibitors (NRTI) plus an HIV protease inhibitor (PI), have been widely used since 1996. They produce durable suppression of viral replication with undetectable plasma levels of HIV-RNA in more than half of patients.
Flepp, Markus, Schiffer, V., Weber, R., Hirschel, Bernard   +3 more
openaire   +4 more sources

New findings on the d(TGGGAG) sequence: Surprising anti-HIV-1 activity [PDF]

, 2018
The biological relevance of tetramolecular G-quadruplexes especially as anti-HIV agents has been extensively reported in the literature over the last years. In the light of our recent results regarding the slow G-quadruplex folding kinetics of ODNs based
Di Fabio, Giovanni, Liekens, Sandra, Noppen, Sam, Pannecouque, Christophe, Romanucci, Valeria, Zarrelli, Armando   +5 more
core   +1 more source