Results 61 to 70 of about 3,688,101 (379)
Comparative antiviral activity of integrase inhibitors in human monocyte-derived macrophages and lymphocytes [PDF]
, 2011 The activity of raltegravir and 4 other integrase inhibitors (MK-2048, L870,810, IN2, and IN5) was investigated in primary human macrophages, PBMC and C8166-lymphocytic T cells, in order to determine their relative potency and efficacy in different ...
Aquaro, S +6 more
core +1 more source
Zhongguo shuxue zazhiObjective To evaluate the quality of laboratory testing using anti-HIV ELISA quality monitoring indicators and continuously improve laboratory testing capabilities.
Jing LIU, Jingjing WANG, Yanmei ZHAO
doaj +1 more source
Potential Anti-HIV Agents from Marine Resources: An Overview
Marine Drugs, 2010 Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/AIDS patients.
Thanh-Sang Vo, Se-Kwon Kim
doaj +1 more source
Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]
, 2014 The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA +4 more
core +1 more source
HIV Medicine, 2018 Previous studies have suggested that hypertension in HIV‐positive individuals is associated primarily with traditional risk factors such as older age, diabetes and dyslipidaemia. However, controversy remains as to whether exposure to antiretroviral (ARV)
C. Hatleberg +13 more
semanticscholar +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Medicine ScienceDespite the increase in preventive health measures and awareness-raising efforts against HIV worldwide, it continues to be a significant global public health problem today.
Hacer Ozlem Kalayci +3 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
HIV screening results of college group blood donors in Tianjin from 2012 to 2021
Zhongguo shuxue zazhi, 2022 Objective To analyze the infection characteristics and prevalence of HIV among college group voluntary blood donors in Tianjin, China, so as to provide data support for improving the promotion and recruitment strategies of voluntary blood donors ...
Caixia SHI, Jing FAN, Xue CHENG, Rui LIU
doaj +1 more source
HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors [PDF]
, 2005 RNA and DNA aptamers specific for HIV-1 reverse transcriptase (RT) can inhibit reverse transcription in vitro. RNA aptamers have been shown to potently block HIV-1 replication in culture.
Fisher, Timothy S +2 more
core +3 more sources