Results 191 to 200 of about 295,334 (238)

Mechanistic Insights and Therapeutic Potentials of Ubiquitin‐Proteasome System in Non‐Small Cell Lung Cancer

Cell Proliferation, EarlyView.
Lung cancer development involves mechanisms like reduced EGFR/EGF ubiquitination driving cancer cell behaviors and immune evasion via loss of PD‐1/PD‐L1 ubiquitination. Balancing ubiquitination and deubiquitination may be a potential therapeutic strategy. ABSTRACT Non‐small cell lung cancer (NSCLC) remains a leading cause of cancer mortality.
Guangyao Zhou, Jiaxiong Tan, Pengpeng Zhang, Zhaokai Zhou, Lianmin Zhang, Zhenfa Zhang   +5 more
wiley   +1 more source

Neuropathogenesis of acute HIV: mechanisms, biomarkers, and therapeutic approaches. [PDF]

Curr Opin HIV AIDS
Jia FF, Brew BJ.
europepmc   +1 more source

Transitional changes in medication‐initiator cohort profiles in persons with chronic kidney disease and type 2 diabetes—A hospital‐based cohort study in Japan

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To describe temporal changes in the characteristics of medication‐initiator cohorts in persons with chronic kidney disease (CKD) and type 2 diabetes (T2D). Materials and Methods Adults with CKD and T2D initiating sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i) or glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) were identified in ...
Yuichiro Yano, Suguru Okami, Hiroshi Kanegae, Nikolaus G. Oberprieler, Catherine Johannes, Satoshi Yamashita, Kanae Yoshikawa‐Ryan, Csaba P. Kovesdy, David Vizcaya, Naoki Kashihara   +9 more
wiley   +1 more source

Evaluation of the Potency of Repurposed Antiretrovirals in HBV Therapy: A Narrative Investigation of the Traditional Medicine Alternatives. [PDF]

Int J Mol Sci
Ugbaja SC, Mokoena AT, Mushebenge AG, Kumalo HM, Ngcobo M, Gqaleni N.   +5 more
europepmc   +1 more source

Challenges of concurrent HIV infection in the course and management of Crohn's disease. [PDF]

J Med Life
Mattar L, Thalib HI, Alnuwaimi M, Alsaadi H, Allouji HA, Alyafei J, Alshowiman L, Alsobyani N, Hassan FES.   +8 more
europepmc   +1 more source

Infection Risk and Vaccination in the Management of Psoriasis: Considerations for Biologic Therapy. [PDF]

Psoriasis (Auckl)
Mateu-Arrom L, Puig L.
europepmc   +1 more source

Candidal speciation and carriage in oral cavity of HIV-positive children/adults and healthy individuals in the South Canara district of India: a comparative study. [PDF]

BMC Res Notes
Ks S, Natarajan S, Boaz K, Baliga S, Ramapuram J, Solomon MC, Manaktala N, Chitra NS.   +7 more
europepmc   +1 more source

The Human Milk Oligosaccharide Lacto-N-Fucopentaose III Conjugated to Dextran Inhibits HIV Replication in Primary Human Macrophages. [PDF]

Nutrients
Media TS, Ramesh M, Lee OI, Ubaka LN, Harn DA, Norberg T, Quinn F, Garg A.   +7 more
europepmc   +1 more source

Liquid Chromatography-Mass Spectrometry Metabolomic Analysis of <i>Terminalia ferdinandiana</i> Exell. Fruit Extracts That Inhibit HIV-1 Cell Infection, HIV-1 Reverse Transcriptase and HIV-1 Protease. [PDF]

Molecules
Cock IE, Matthews B, Basson AE.
europepmc   +1 more source

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Alkaloids as Potential Anti-HIV Agents

Current HIV Research, 2023
Background: Alkaloids are nitrogen-containing compounds that are naturally occurring and have a variety of biological activities, including antimicrobial properties. In this study, the authors used a molecular docking approach to evaluate the anti-HIV potential of 64 alkaloids.
Nidhi, Rani, Randhir, Singh, Praveen, Kumar, Prerna, Sharma, Rajwinder, Kaur, Rashmi, Arora, Thakur Gurjeet, Singh   +6 more
openaire   +2 more sources