Results 61 to 70 of about 241,196 (260)
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Pre-exposure prophylaxis (PrEP) for HIV prevention [PDF]
Pre-exposure prophylaxis, or PrEP, is a way for people who do not have HIV to help prevent HIV infection by taking a pill every day. The pill contains two medicines that are also used, in combination with other medicines, to treat HIV.
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British Journal of Clinical Pharmacology, EarlyView.Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie +10 more
wiley +1 more source
Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents. [PDF]
Iran J Pharm Res, 2021 Imani A +4 more
europepmc +1 more source
Biopharmaceutics &Drug Disposition, EarlyView.Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula +4 more
wiley +1 more source
Anti-Human Immunodeficiency Virus (HIV) Agents
, 2005 This article gives a brief review of anti-retroviral agents with activity against the Human Immunodeficiency Virus (HIV) the causative agen of Acquired Immunodeficiency Syndrome (AIDS).
Okolie, MN +5 more
core +1 more source
Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions
Biotechnology and Bioengineering, EarlyView.ABSTRACT To advance understanding of cellular metabolism and reduce batch‐to‐batch variability in cell culture processes, this study introduces a multi‐scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell cultures undergoing metabolic phase transitions.
Keqi Wang, Sarah W. Harcum, Wei Xie
wiley +1 more source
Report of the NIH Panel to Define Principles of Therapy of HIV Infection [PDF]
Report of the NIH Panel to Define Principles of Therapy of HIV Infection: Recent research advances have afforded substantially improved understanding of the biology of human immunodeficiency virus (HIV) infection and the pathogenesis of the acquired ...
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Personalizing HIV therapy, mission impossible?
, 2013 Sustained HIV suppression depends on a number of factors including therapy adherence, management of side effects, viral resistance and individual characteristics of patients and therapeutic settings.
Hentig, Nils von
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Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source