Results 61 to 70 of about 242,381 (303)

Molecular monitoring of HIV-1 drug resistance in Ifakara HIV-1 Cohort, Tanzania [PDF]

open access: yes, 2013
HIV-1 resistance is one of the problems affecting success of antiretroviral therapy programmes worldwide. Many studies on efficacy of ART programmes, specifically on drug resistance, have been conducted in developed countries but not in developing ...
Masimba, Pax Jessey
core   +1 more source

Antibacterial, Anti-HIV-1 Protease and Cytotoxic Activities of Aqueous Ethanolic Extracts from Combretum Adenogonium Steud. Ex A. Rich (Combretaceae). [PDF]

open access: yes, 2012
\ud \ud Records have shown that Combretum adenogonium Steud. Ex A. Rich (Combretaceae) is used in traditional medicine systems of several tribes in Tanzania. This study focused on the investigation of antibacterial activity, anti-HIV-1 protease activity,
Innocent Ester   +11 more
core   +1 more source

Seroprevalence of Hepatitis B, Hepatitis C and HIV in Intensive Care Unit Patients

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2015
Objective: Intensive care unit (ICU) personnel are at high risk for infectious agents during interventional procedures, surgical procedures, and processes such as injection.
Hakan Bayır   +4 more
doaj   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula   +4 more
wiley   +1 more source

Marine Algae Metabolites as Promising Therapeutics for the Prevention and Treatment of HIV/AIDS

open access: yesMetabolites, 2019
This review presents an analysis of works devoted to the anti-human immunodeficiency virus (HIV) activity of algae metabolites—sulfated polysaccharides (fucoidans, carrageenans), lectins, laminarans, and polyphenols.
Natalya N. Besednova   +7 more
doaj   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise   +3 more
wiley   +1 more source

Anti-Human Immunodeficiency Virus (HIV) Agents [PDF]

open access: yes, 2005
This article gives a brief review of anti-retroviral agents with activity against the Human Immunodeficiency Virus (HIV) the causative agen of Acquired Immunodeficiency Syndrome (AIDS).
Okolie, MN   +5 more
core   +1 more source

Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

open access: yesNature Communications, 2017
Tuberculosis (TB) remains one of the world’s deadliest communicable diseases, novel anti-TB agents are urgently needed due to severe drug resistance and the co-epidemic of TB/HIV.
Junying Ma   +10 more
doaj   +1 more source

Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils

open access: yesBiology Open, 2015
Semen harbors amyloid fibrils formed by proteolytic fragments of prostatic acid phosphatase (PAP248-286 and PAP85-120) and semenogelins (SEM1 and SEM2) that potently enhance HIV infectivity.
Laura M. Castellano   +4 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

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