Increased prescription rate of anti‐infective agents after diagnosis of myelodysplastic syndromes [PDF]
The a priori risk for infections in patients with myelodysplastic syndromes (MDS) is unknown. This study examines prescription rates of anti‐infective agents in MDS patients before and after diagnosis, in both in‐ and outpatient settings, to provide ...
Johanne Rozema+8 more
doaj +7 more sources
Pharmacokinetics of anti-infective agents during CytoSorb hemoadsorption [PDF]
Cytokine hemoadsorption might be beneficial in patients with sepsis. However, its effect on anti-infective agents' disposition remains largely unknown.
Antoine G. Schneider+6 more
doaj +7 more sources
Small and Versatile Cyclotides as Anti-infective Agents. [PDF]
Plants provide an abundant source of potential therapeutic agents, including a diverse array of compounds, such as cyclotides, which are peptides known for their antimicrobial activity. Cyclotides are multifaceted molecules with a wide range of biological activities.
Cândido ES+7 more
europepmc +4 more sources
Editorial: Inspired by Nature: Towards Novel Anti-Infective Agents [PDF]
Ricardo J. Ferreira+5 more
doaj +4 more sources
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents [PDF]
This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina+3 more
doaj +2 more sources
Impact of High-Dose Anti-Infective Agents on the Osteogenic Response of Mesenchymal Stem Cells [PDF]
Treatment of infected nonunions and severe bone infections is a huge challenge in modern orthopedics. Their treatment routinely includes the use of anti-infective agents. Although frequently used, little is known about their impact on the osteogenesis of
Jakob Hofmann+4 more
doaj +2 more sources
Dose Optimization and Targeting Strategies of Anti-Infective Agents [PDF]
Most drugs are currently developed, approved and marketed based on their effect on the majority of the population [...]
Martin Šíma, Ondřej Slanař
doaj +2 more sources
Use of T Cell Mediated Immune Functional Assays for Adjustment of Immunosuppressive or Anti-infective Agents in Solid Organ Transplant Recipients: A Systematic Review [PDF]
Background: Defining the optimal dosage of the immunosuppressive or duration of anti-infective agents is a challenge in solid organ transplant (SOT) recipients.
Omid Rezahosseini+13 more
doaj +2 more sources
Thienopyrimidine: A Promising Scaffold to Access Anti-Infective Agents [PDF]
Thienopyrimidines are widely represented in the literature, mainly due to their structural relationship with purine base such as adenine and guanine. This current review presents three isomers—thieno[2,3-d]pyrimidines, thieno[3,2-d]pyrimidines and thieno[
Prisca Lagardère+3 more
doaj +2 more sources