Results 41 to 50 of about 163,167 (287)
Brazilian Oral Research, 2017 The aim of this study was to develop an experimental adhesive with addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride (METAC) and to evaluate its mechanical and biological properties and its in vitro antibacterial activity.
Fabrício Mezzomo COLLARES +5 more
doaj +1 more source
Zaporožskij Medicinskij Žurnal, 2015 Aim. A number of new 3,5-R-4-(3-(5-nitrofuran-2-yl)allylidenami-no)-1-R1-4H-1,2,4-triazole halides have been synthesized, the structure of synthesized compounds has been proved by modern physical-chemical methods. Methods and results.
T. S. Brytanova +4 more
doaj +1 more source
Public contributions to the development of antibiotics: two successful and two failed investments
Journal of Pharmaceutical Policy and PracticeBackground The aim is to showcase a detailed analysis of the contribution of public funding to two successful (gepotidacin and zoliflodacin) and two failed (epetraborole and ridnilazole) public sector investments in antibiotic development, using a ...
Louise Schmidt +3 more
doaj +1 more source
Journal of Applied Oral Science, 2008 OBJECTIVE: The aim of the present study was to determine the in vitro maximum inhibitory dilution (MID) of two chlorhexidinebased oral mouthwashes (CHX): Noplak®, Periogard®, and one polyhexamethylene biguanide-based mouthwash (PHMB): Sanifill Premium ...
Andresa Piacezzi Nascimento +5 more
doaj +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
‘Piloting a framework for analysing the public contributions to R&D: new antibiotics in focus’
Journal of Pharmaceutical Policy and PracticeBackground Within the context of increasing transparency around public contributions, a framework for reporting and analysing public contributions to research and development (R&D) was previously developed and is piloted here using the example of ...
Louise Schmidt +4 more
doaj +1 more source
Arylsulphones: A Promising Class on Non-Nucleoside Antiviral Agents [PDF]
, 2005 The design and development of antiviral agents are an urgent need. The continuing problem associated with the emergence of drug resistant strains stimulates for new compounds for the treatment of both chronic diseases and acute infections.
GARUTI, LAURA +3 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Thiourethane-functionalized fillers: biological properties and degradation resistance [PDF]
Brazilian Oral ResearchThis study determined the effect of thiourethane-functionalized fillers (TU) on the antimicrobial properties, cytotoxicity, degree of conversion (DC), water sorption (Wsp) and solubility (Wsl) of experimental composites. TU-modified fillers were added at
Larissa Maria CAVALCANTE +6 more
doaj +2 more sources
Anti-infective effects o Lactobacilli in the gastrointestinal tract [PDF]
, 2003 Antibiotics constitute the dominant treatment of gastrointestinal infections. However, several serious side-effects are associated with extensive use of antibiotics, including spread of bacterial resistance and allergic reactions as well as potential ...
Thorlacius, Henrik, +2 more
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